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    SRRM2-AS1 SRRM2 antisense RNA 1 [ Homo sapiens (human) ]

    Gene ID: 100128788, updated on 17-Jun-2024

    Summary

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    Official Symbol
    SRRM2-AS1provided by HGNC
    Official Full Name
    SRRM2 antisense RNA 1provided by HGNC
    Primary source
    HGNC:HGNC:44162
    See related
    Ensembl:ENSG00000205913 AllianceGenome:HGNC:44162
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Biased expression in testis (RPKM 4.9), prostate (RPKM 0.4) and 2 other tissues See more
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    Genomic context

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    See SRRM2-AS1 in Genome Data Viewer
    Location:
    16p13.3
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (2737076..2752600, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (2757295..2772815, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (2787077..2802601, complement)

    Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7065 Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:2732882-2733492 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10278 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10279 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:2738809-2739397 Neighboring gene potassium channel tetramerization domain containing 5 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:2742501-2743319 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:2743320-2744137 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7066 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7067 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7068 Neighboring gene serine protease 27 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:2770495-2771062 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7070 Neighboring gene ReSE screen-validated silencer GRCh37_chr16:2772439-2772608 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:2788581-2789158 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancers GRCh37_chr16:2801519-2802361 and GRCh37_chr16:2802362-2803204 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:2803205-2804047 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr16:2807529-2808728 Neighboring gene serine/arginine repetitive matrix 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:2819013-2819715 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:2819716-2820419 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:2820420-2821122 Neighboring gene ReSE screen-validated silencer GRCh37_chr16:2823070-2823222 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7073 Neighboring gene elongin B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Silencing of long noncoding RNA SRRM2-AS exerts suppressive effects on angiogenesis in nasopharyngeal carcinoma via activating MYLK-mediated cGMP-PKG signaling pathway. Chen S, et al. J Cell Physiol, 2020 Nov. PMID 31742692
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Silencing of long noncoding RNA SRRM2-AS exerts suppressive effects on angiogenesis in nasopharyngeal carcinoma via activating MYLK-mediated cGMP-PKG signaling pathway.
      Title: Silencing of long noncoding RNA SRRM2-AS exerts suppressive effects on angiogenesis in nasopharyngeal carcinoma via activating MYLK-mediated cGMP-PKG signaling pathway.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    General gene information

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    Markers

    Other Names

    • CTD-2270P14.3
    • SRRM2 antisense RNA 1 (non-protein coding)

    Clone Names

    • FLJ25760, FLJ31501

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_027274.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) is the longer transcript.
      Source sequence(s)
      AK056063, AK098626
      Related
      ENST00000571305.5

    2. NR_027275.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' sequence and an internal region, as compared to variant 1.
      Source sequence(s)
      AK056063, AK098626, DB448439
      Related
      ENST00000573802.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

      Range
      2737076..2752600 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060940.1 Alternate T2T-CHM13v2.0

      Range
      2757295..2772815 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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