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    Ankdd1a ankyrin repeat and death domain containing 1A [ Mus musculus (house mouse) ]

    Gene ID: 330963, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Ankdd1aprovided by MGI
    Official Full Name
    ankyrin repeat and death domain containing 1Aprovided by MGI
    Primary source
    MGI:MGI:2686319
    See related
    Ensembl:ENSMUSG00000066510 AllianceGenome:MGI:2686319
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm1473; EG330963; A730067D02; A730067D02Rik
    Summary
    Orthologous to human ANKDD1A (ankyrin repeat and death domain containing 1A). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in bladder adult (RPKM 3.9), CNS E18 (RPKM 0.4) and 4 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Ankdd1a in Genome Data Viewer
    Location:
    9 C; 9 35.35 cM
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (65395746..65427691, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (65488464..65520412, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene RAS-like, family 12 Neighboring gene solute carrier family 51, beta subunit Neighboring gene STARR-positive B cell enhancer ABC_E6755 Neighboring gene STARR-positive B cell enhancer ABC_E2295 Neighboring gene mitochondrial methionyl-tRNA formyltransferase Neighboring gene STARR-positive B cell enhancer ABC_E2895 Neighboring gene SPG21, maspardin Neighboring gene STARR-seq mESC enhancer starr_24454 Neighboring gene predicted gene, 17749 Neighboring gene STARR-positive B cell enhancer ABC_E2896 Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:65389334-65389517 Neighboring gene STARR-positive B cell enhancer ABC_E2897 Neighboring gene STARR-positive B cell enhancer ABC_E9331 Neighboring gene pleckstrin homology domain containing, family O member 2 Neighboring gene STARR-seq mESC enhancer starr_24458 Neighboring gene STARR-positive B cell enhancer ABC_E892

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    2. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    ankyrin repeat and death domain-containing protein 1A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001370871.1 → NP_001357800.1  ankyrin repeat and death domain-containing protein 1A

      Status: VALIDATED

      Source sequence(s)
      AC114645
      UniProtKB/TrEMBL
      A0A1L1ST07
      Conserved Domains (4) summary
      PHA03095
      Location:96 → 368
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:149 → 179
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:19 → 108
      Ank_2; Ankyrin repeats (3 copies)
      cl14633
      Location:420 → 491
      DD; Death Domain Superfamily of protein-protein interaction domains

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      65395746..65427691 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036155086.1 → XP_036010979.1  ankyrin repeat and death domain-containing protein 1A isoform X1

      UniProtKB/TrEMBL
      A0A1L1ST07
      Conserved Domains (3) summary
      PHA03095
      Location:96 → 368
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:149 → 179
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:19 → 108
      Ank_2; Ankyrin repeats (3 copies)

    2. XM_006511596.4 → XP_006511659.1  ankyrin repeat and death domain-containing protein 1A isoform X5

      See identical proteins and their annotated locations for XP_006511659.1

      UniProtKB/TrEMBL
      A0A1L1ST07
      Conserved Domains (3) summary
      PHA03095
      Location:96 → 368
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:149 → 179
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:19 → 108
      Ank_2; Ankyrin repeats (3 copies)

    3. XM_036155087.1 → XP_036010980.1  ankyrin repeat and death domain-containing protein 1A isoform X4

      UniProtKB/TrEMBL
      A0A1L1ST07
      Conserved Domains (3) summary
      PHA03095
      Location:96 → 368
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:149 → 179
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:19 → 108
      Ank_2; Ankyrin repeats (3 copies)

    4. XM_017313713.3 → XP_017169202.1  ankyrin repeat and death domain-containing protein 1A isoform X2

      UniProtKB/TrEMBL
      A0A1L1ST07
      Related
      ENSMUSP00000150130.2, ENSMUST00000217646.2
      Conserved Domains (4) summary
      PHA03095
      Location:96 → 368
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:149 → 179
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:19 → 108
      Ank_2; Ankyrin repeats (3 copies)
      cl14633
      Location:420 → 491
      DD; Death Domain Superfamily of protein-protein interaction domains

    5. XM_017313714.3 → XP_017169203.1  ankyrin repeat and death domain-containing protein 1A isoform X3

      UniProtKB/TrEMBL
      A0A1L1ST07
      Related
      ENSMUSP00000057040.6, ENSMUST00000061766.6
      Conserved Domains (3) summary
      PHA03095
      Location:96 → 368
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:149 → 179
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:19 → 108
      Ank_2; Ankyrin repeats (3 copies)

    6. XM_006511599.5 → XP_006511662.1  ankyrin repeat and death domain-containing protein 1A isoform X6

      See identical proteins and their annotated locations for XP_006511662.1

      Conserved Domains (3) summary
      PHA03095
      Location:96 → 368
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:149 → 179
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:19 → 108
      Ank_2; Ankyrin repeats (3 copies)

    RNA

    1. XR_001779211.3 RNA Sequence

    2. XR_870872.3 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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