pipp-4P Phosphatidylinositol-4,5-bisphosphate 4-phosphatase [Caenorhabditis elegans] - Gene

Summary

Gene symbol: pipp-4P
Gene description: Phosphatidylinositol-4,5-bisphosphate 4-phosphatase
Locus tag: CELE_Y71H2AM.2
See related: AllianceGenome:WB:WBGene00022167
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity. Predicted to be involved in phosphatidylinositol dephosphorylation. Predicted to be located in endosome membrane and lysosome. Predicted to be integral component of membrane. Predicted to be active in bounding membrane of organelle and plasma membrane. Orthologous to several human genes including PIP4P1 (phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1). [provided by Alliance of Genome Resources, Apr 2022]
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Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity	IBA Inferred from Biological aspect of Ancestor more info
enables phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in phosphatidylinositol dephosphorylation	IBA Inferred from Biological aspect of Ancestor more info
involved_in phosphatidylinositol dephosphorylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in endosome	IEA Inferred from Electronic Annotation more info
is_active_in late endosome membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in late endosome membrane	IEA Inferred from Electronic Annotation more info
is_active_in lysosomal membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in lysosomal membrane	IEA Inferred from Electronic Annotation more info
located_in lysosome	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in phagocytic vesicle membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

NP_001411904.1

NP_497624.3

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The following sections contain reference sequences that belong to a specific genome build. Explain

NM_001424978.1 → NP_001411904.1 Phosphatidylinositol-4,5-bisphosphate 4-phosphatase [Caenorhabditis elegans]

Status: REVIEWED
NM_065223.6 → NP_497624.3 Phosphatidylinositol-4,5-bisphosphate 4-phosphatase [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_497624.3

Status: REVIEWED

UniProtKB/TrEMBL

Q9BL29

Conserved Domains (1) summary

pfam09788
Location:59 → 217

Tmemb_55A; Transmembrane protein 55A