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    Ccdc69 coiled-coil domain containing 69 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 497906, updated on 6-Jun-2024

    Summary

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    Official Symbol
    Ccdc69provided by RGD
    Official Full Name
    coiled-coil domain containing 69provided by RGD
    Primary source
    RGD:1562251
    See related
    Ensembl:ENSRNOG00000021370 AllianceGenome:RGD:1562251
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1562251
    Summary
    Predicted to enable microtubule binding activity. Predicted to be involved in spindle midzone assembly. Predicted to be located in spindle midzone. Predicted to be active in nucleus. Predicted to colocalize with cytoplasm. Orthologous to human CCDC69 (coiled-coil domain containing 69). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Spleen (RPKM 64.0), Thymus (RPKM 61.0) and 7 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ccdc69 in Genome Data Viewer
    Location:
    10q22
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (39673984..39701080, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (39173282..39200358, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (40392459..40419567, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene annexin A6 Neighboring gene uncharacterized LOC120095102 Neighboring gene Y box binding protein 1, pseudogene 20 Neighboring gene ganglioside GM2 activator Neighboring gene uncharacterized LOC134480794 Neighboring gene solute carrier family 36, member 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Role of a novel coiled-coil domain-containing protein CCDC69 in regulating central spindle assembly. Pal D, et al. Cell Cycle, 2010 Oct 15. PMID 20962590, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in spindle midzone assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    colocalizes_with cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in spindle midzone ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    coiled-coil domain-containing protein 69

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109031.1 → NP_001102501.1  coiled-coil domain-containing protein 69

      See identical proteins and their annotated locations for NP_001102501.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473948
      UniProtKB/TrEMBL
      A0A8I6AK54, A6HEK7, A6HEK8, D3ZTN8
      Related
      ENSRNOP00000037400.4, ENSRNOT00000039040.5

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      39673984..39701080 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006246395.5 → XP_006246457.1  coiled-coil domain-containing protein 69 isoform X4

      UniProtKB/TrEMBL
      A0A8I6AK54, A6HEK8

    2. XM_063269609.1 → XP_063125679.1  coiled-coil domain-containing protein 69 isoform X1

      UniProtKB/TrEMBL
      A0A8I6AK54, A6HEK8

    3. XM_006246393.4 → XP_006246455.1  coiled-coil domain-containing protein 69 isoform X2

      See identical proteins and their annotated locations for XP_006246455.1

      UniProtKB/TrEMBL
      A0A8I6AK54, A6HEK8

    4. XM_039086564.2 → XP_038942492.1  coiled-coil domain-containing protein 69 isoform X6

    5. XM_063269611.1 → XP_063125681.1  coiled-coil domain-containing protein 69 isoform X6

    6. XM_063269610.1 → XP_063125680.1  coiled-coil domain-containing protein 69 isoform X5

    7. XM_006246394.5 → XP_006246456.1  coiled-coil domain-containing protein 69 isoform X3

    RNA

    1. XR_005489904.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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