esyt3 extended synaptotagmin-like protein 3 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: esyt3provided by ZNC
Official Full Name: extended synaptotagmin-like protein 3provided by ZNC
Primary source: ZFIN:ZDB-GENE-050809-35
See related: Ensembl:ENSDARG00000006422 AllianceGenome:ZFIN:ZDB-GENE-050809-35
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: FAM62A; im:7153182; si:ch211-219a4.7
Summary: Predicted to enable calcium ion binding activity and phospholipid binding activity. Predicted to act upstream of or within endoplasmic reticulum-plasma membrane tethering and lipid transport. Predicted to be located in endoplasmic reticulum and plasma membrane. Predicted to be integral component of membrane. Predicted to be extrinsic component of cytoplasmic side of plasma membrane and intrinsic component of endoplasmic reticulum membrane. Orthologous to human ESYT3 (extended synaptotagmin 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 9

Exon count:: 23

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	9	NC_007120.7 (23783856..23807032, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	9	NC_007120.6 (23972987..23996163, complement)

Chromosome 9 - NC_007120.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables calcium ion binding	IBA Inferred from Biological aspect of Ancestor more info
enables calcium-dependent phospholipid binding	IBA Inferred from Biological aspect of Ancestor more info
enables lipid binding	IEA Inferred from Electronic Annotation more info
enables phosphatidylcholine binding	IBA Inferred from Biological aspect of Ancestor more info
enables phosphatidylethanolamine binding	IBA Inferred from Biological aspect of Ancestor more info
enables phosphatidylinositol binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within endoplasmic reticulum-plasma membrane tethering	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within lipid transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
is_active_in endoplasmic reticulum membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: extended synaptotagmin-3

Names: fam62c

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001123233.1 → NP_001116705.1 extended synaptotagmin-3

Status: PROVISIONAL

Source sequence(s)

CR533429

UniProtKB/TrEMBL

A0A8M1NG28, B0UYL4

Related

ENSDARP00000010917.7, ENSDART00000027443.8

Conserved Domains (4) summary

cd04030
Location:726 → 850

C2C_KIAA1228; C2 domain third repeat present in uncharacterized human KIAA1228-like proteins

cd04050
Location:443 → 567

C2B_Synaptotagmin-like; C2 domain second repeat present in Synaptotagmin-like proteins

cd08391
Location:302 → 422

C2A_C2C_Synaptotagmin_like; C2 domain first and third repeat in Synaptotagmin-like proteins

pfam17047
Location:109 → 287

SMP_LBD; Synaptotagmin-like mitochondrial-lipid-binding domain