Ssxb3 SSX member B3 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Ssxb3provided by MGI
Official Full Name: SSX member B3provided by MGI
Primary source: MGI:MGI:2446772
See related: Ensembl:ENSMUSG00000079701 AllianceGenome:MGI:2446772
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary: Predicted to enable transcription corepressor activity. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in synovial sarcoma. Orthologous to several human genes including SSX1 (SSX family member 1); SSX2B (SSX family member 2B); and SSX3 (SSX family member 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Low expression observed in reference dataset See more
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Genomic context

Location:: X A1.1; X 3.89 cM

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	X	NC_000086.8 (8449643..8458055, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	X	NC_000086.7 (8583404..8591816, complement)

Chromosome X - NC_000086.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables transcription corepressor activity	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	ISO Inferred from Sequence Orthology more info
located_in sperm flagellum	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: synovial sarcoma, X member B3

Names: synovial sarcoma, X member B, breakpoint 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_198898.3 → NP_942601.1 synovial sarcoma, X member B3

See identical proteins and their annotated locations for NP_942601.1

Status: VALIDATED

Source sequence(s)

BX890578

Consensus CDS

CCDS29999.1

UniProtKB/TrEMBL

A2BI93, Q6XAR8, Q6XAS4

Related

ENSMUSP00000086792.5, ENSMUST00000089374.11

Conserved Domains (3) summary

cd07765
Location:24 → 61

KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

smart00349
Location:23 → 78

KRAB; krueppel associated box

pfam09514
Location:139 → 160

SSXRD; SSXRD motif