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    Klrg2 killer cell lectin-like receptor subfamily G, member 2 [ Mus musculus (house mouse) ]

    Gene ID: 74253, updated on 30-Apr-2024

    Summary

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    Official Symbol
    Klrg2provided by MGI
    Official Full Name
    killer cell lectin-like receptor subfamily G, member 2provided by MGI
    Primary source
    MGI:MGI:1921503
    See related
    Ensembl:ENSMUSG00000071537 AllianceGenome:MGI:1921503
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2310020F24Rik
    Summary
    Predicted to enable carbohydrate binding activity. Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human KLRG2 (killer cell lectin like receptor G2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in stomach adult (RPKM 6.9), genital fat pad adult (RPKM 3.0) and 7 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    6 B1; 6 17.85 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (38593264..38615750, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (38616329..38638815, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:38484704-38484891 Neighboring gene STARR-positive B cell enhancer ABC_E2782 Neighboring gene kinesin family member 11 pseudogene Neighboring gene formation of mitochondrial complex V assembly factor 1 Neighboring gene LUC7-like 2 (S. cerevisiae) Neighboring gene Clec2l Hedgehog-responsive enhancer Neighboring gene C-type lectin domain family 2, member L Neighboring gene homeodomain interacting protein kinase 2 Neighboring gene predicted gene, 53285

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
    2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
    5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    killer cell lectin-like receptor subfamily G member 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033171.2 → NP_001028343.2  killer cell lectin-like receptor subfamily G member 2

      See identical proteins and their annotated locations for NP_001028343.2

      Status: VALIDATED

      Source sequence(s)
      AC161147, AK009417
      Consensus CDS
      CCDS20016.1
      UniProtKB/Swiss-Prot
      Q3TE30, Q3UM83
      UniProtKB/TrEMBL
      G5E8L6
      Related
      ENSMUSP00000093732.4, ENSMUST00000096030.7
      Conserved Domains (1) summary
      cd03593
      Location:271 → 382
      CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      38593264..38615750 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006506711.4 → XP_006506774.1  killer cell lectin-like receptor subfamily G member 2 isoform X1

      UniProtKB/Swiss-Prot
      Q3TE30, Q3UM83
      Conserved Domains (2) summary
      PHA03247
      Location:4 → 197
      PHA03247; large tegument protein UL36; Provisional
      cl02432
      Location:271 → 350
      CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3UM83.1 GenPept UniProtKB/Swiss-Prot:Q3UM83

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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