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    Rassf7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 [ Mus musculus (house mouse) ]

    Gene ID: 66985, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Rassf7provided by MGI
    Official Full Name
    Ras association (RalGDS/AF-6) domain family (N-terminal) member 7provided by MGI
    Primary source
    MGI:MGI:1914235
    See related
    Ensembl:ENSMUSG00000038618 AllianceGenome:MGI:1914235
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2400009B11Rik
    Summary
    Predicted to be involved in regulation of microtubule cytoskeleton organization and signal transduction. Predicted to act upstream of or within apoptotic process. Predicted to be located in centriolar satellite. Is expressed in epidermis; gut; respiratory system; and urinary system. Orthologous to human RASSF7 (Ras association domain family member 7). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in colon adult (RPKM 67.0), duodenum adult (RPKM 54.6) and 24 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    7 F5; 7 86.51 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (140795338..140798571)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (141215425..141218658)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E9115 Neighboring gene STARR-positive B cell enhancer ABC_E11375 Neighboring gene Harvey rat sarcoma virus oncogene Neighboring gene leucine rich repeat containing 56 Neighboring gene STARR-positive B cell enhancer ABC_E1749 Neighboring gene lamin tail domain containing 2 Neighboring gene STARR-positive B cell enhancer ABC_E2854 Neighboring gene microRNA 210 Neighboring gene STARR-positive B cell enhancer ABC_E11376 Neighboring gene predicted gene, 51460 Neighboring gene PHD and ring finger domains 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
    2. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
    3. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in centriolar satellite ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ras association domain-containing protein 7
    Names
    Ras association (RalGDS/AF-6) domain family 7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025886.3 → NP_080162.3  ras association domain-containing protein 7

      See identical proteins and their annotated locations for NP_080162.3

      Status: VALIDATED

      Source sequence(s)
      AK010305, AW990538, CK617449
      Consensus CDS
      CCDS40182.1
      UniProtKB/Swiss-Prot
      Q9DD19
      UniProtKB/TrEMBL
      A0A1B0GRE0
      Related
      ENSMUSP00000038444.6, ENSMUST00000046890.12
      Conserved Domains (2) summary
      TIGR02168
      Location:158 → 334
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd16135
      Location:8 → 90
      RA_RASSF7; Ras-associating (RA) domain found in N-terminal Ras-association domain family 7 (RASSF7)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      140795338..140798571
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006536228.4 → XP_006536291.1  ras association domain-containing protein 7 isoform X1

      See identical proteins and their annotated locations for XP_006536291.1

      UniProtKB/Swiss-Prot
      Q9DD19
      UniProtKB/TrEMBL
      A0A1B0GRE0
      Conserved Domains (2) summary
      TIGR02168
      Location:158 → 334
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd16135
      Location:8 → 90
      RA_RASSF7; Ras-associating (RA) domain found in N-terminal Ras-association domain family 7 (RASSF7)

    2. XM_006536226.5 → XP_006536289.1  ras association domain-containing protein 7 isoform X1

      See identical proteins and their annotated locations for XP_006536289.1

      UniProtKB/Swiss-Prot
      Q9DD19
      UniProtKB/TrEMBL
      A0A1B0GRE0
      Conserved Domains (2) summary
      TIGR02168
      Location:158 → 334
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd16135
      Location:8 → 90
      RA_RASSF7; Ras-associating (RA) domain found in N-terminal Ras-association domain family 7 (RASSF7)

    3. XM_006536227.5 → XP_006536290.1  ras association domain-containing protein 7 isoform X1

      See identical proteins and their annotated locations for XP_006536290.1

      UniProtKB/Swiss-Prot
      Q9DD19
      UniProtKB/TrEMBL
      A0A1B0GRE0
      Conserved Domains (2) summary
      TIGR02168
      Location:158 → 334
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd16135
      Location:8 → 90
      RA_RASSF7; Ras-associating (RA) domain found in N-terminal Ras-association domain family 7 (RASSF7)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9DD19.2 GenPept UniProtKB/Swiss-Prot:Q9DD19

    Gene LinkOut

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