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    stk17al serine/threonine kinase 17a like [ Danio rerio (zebrafish) ]

    Gene ID: 777621, updated on 27-Mar-2024

    Summary

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    Official Symbol
    stk17alprovided by ZNC
    Official Full Name
    serine/threonine kinase 17a likeprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-061103-427
    See related
    Ensembl:ENSDARG00000015922 AllianceGenome:ZFIN:ZDB-GENE-061103-427
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fi11h05; fi32b12; wu:fi11h05; wu:fi32b12; zgc:153952
    Summary
    Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and positive regulation of apoptotic process. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in nucleus. Orthologous to human STK17B (serine/threonine kinase 17b). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (16841939..16872909)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (16692154..16723109)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene si:dkey-30j10.5 Neighboring gene leucine rich repeat containing 3Cb Neighboring gene ATPase H+ transporting V0 subunit a1a Neighboring gene caveolae associated protein 1a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. IRF4 drives clonal evolution and lineage choice in a zebrafish model of T-cell lymphoma. Amanda S, et al. Nat Commun, 2022 May 3. PMID 35504924, Free PMC Article
    2. Gene expression profiling of granule cells and Purkinje cells in the zebrafish cerebellum. Takeuchi M, et al. J Comp Neurol, 2017 May 1. PMID 27615194
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of apoptotic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    serine/threonine kinase 17a like; serine/threonine-protein kinase 17A
    NP_001071197.1
    XP_017210081.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001077729.1 → NP_001071197.1  serine/threonine kinase 17a like

      See identical proteins and their annotated locations for NP_001071197.1

      Status: PROVISIONAL

      Source sequence(s)
      BC125921
      UniProtKB/TrEMBL
      A0A8M1NC43, A0JML4
      Related
      ENSDARP00000010065.8, ENSDART00000023985.10
      Conserved Domains (2) summary
      smart00220
      Location:27 → 285
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cl21453
      Location:16 → 285
      PKc_like; Protein Kinases, catalytic domain

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      16841939..16872909
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017354592.2 → XP_017210081.1  serine/threonine-protein kinase 17A isoform X1

      UniProtKB/TrEMBL
      A0A8M1NC43, A0JML4
      Conserved Domains (2) summary
      smart00220
      Location:27 → 285
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cl21453
      Location:16 → 285
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version

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