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    LY86-AS1 LY86 antisense RNA 1 [ Homo sapiens (human) ]

    Gene ID: 285780, updated on 10-Oct-2023

    Summary

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    Official Symbol
    LY86-AS1provided by HGNC
    Official Full Name
    LY86 antisense RNA 1provided by HGNC
    Primary source
    HGNC:HGNC:26593
    See related
    Ensembl:ENSG00000216863 AllianceGenome:HGNC:26593
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    LY86AS; LY86-AS
    Expression
    Biased expression in brain (RPKM 2.1), fat (RPKM 0.2) and 4 other tissues See more
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    Genomic context

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    Location:
    6p25.1
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (6346465..6622826, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (6215377..6492021, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (6346698..6623059, complement)

    Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr6:6169218-6169883 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:6178115-6178614 Neighboring gene coagulation factor XIII A chain Neighboring gene microRNA 7853 Neighboring gene microRNA 5683 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr6:6218631-6219830 Neighboring gene uncharacterized LOC124901253 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23915 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr6:6361855-6363054 Neighboring gene small nuclear RNA activating complex polypeptide 5 pseudogene 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23916 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23917 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23918 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23921 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23920 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23919 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23922 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23923 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23924 Neighboring gene calponin 3 pseudogene 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23925 Neighboring gene ReSE screen-validated silencer GRCh37_chr6:6654090-6654280 Neighboring gene lymphocyte antigen 86 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:6674525-6675024 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr6:6694456-6695405 Neighboring gene uncharacterized LOC101928004 Neighboring gene uncharacterized LOC101928047 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:6712197-6712986 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23927 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:6725016-6725709 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:6750245-6750862 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:6751483-6752100 Neighboring gene uncharacterized LOC105374901

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Long non-coding RNA LY86-AS1 and HCG27_201 expression in type 2 diabetes mellitus. Saeidi L, et al. Mol Biol Rep, 2018 Dec. PMID 30328000
    2. Identification of age- and gender-associated long noncoding RNAs in the human brain with Alzheimer's disease. Cao M, et al. Neurobiol Aging, 2019 Sep. PMID 31280115, Free PMC Article
    3. Epidemiological and genome-wide association study of gastritis or gastric ulcer in korean populations. Oh S, et al. Genomics Inform, 2014 Sep. PMID 25317112, Free PMC Article
    4. A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity. Barnett GC, et al. Radiother Oncol, 2014 May. PMID 24785509
    5. Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies. Shyn SI, et al. Mol Psychiatry, 2011 Feb. PMID 20038947, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity.
    EBI GWAS Catalog
    Epidemiological and genome-wide association study of gastritis or gastric ulcer in korean populations.
    EBI GWAS Catalog
    Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    General gene information

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    Markers

    Other Names

    • LY86 antisense RNA (non-protein coding)
    • LY86 antisense RNA 1 (non-protein coding)

    Clone Names

    • FLJ33708

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_026970.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AK091027, AL133326, BC031936, DA148042
      Related
      ENST00000429345.5

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

      Range
      6346465..6622826 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060930.1 Alternate T2T-CHM13v2.0

      Range
      6215377..6492021 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_173675.1: Suppressed sequence

      Description
      NM_173675.1: This RefSeq was permanently suppressed because it is now thought that this gene does not encode a protein.
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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