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    bnip4 BCL2 interacting protein 4 [ Danio rerio (zebrafish) ]

    Gene ID: 568155, updated on 7-Apr-2024

    Summary

    Official Symbol
    bnip4provided by ZNC
    Official Full Name
    BCL2 interacting protein 4provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-051113-212
    See related
    Ensembl:ENSDARG00000022832 AllianceGenome:ZFIN:ZDB-GENE-051113-212
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    nip3b; wu:fc54d07; zgc:123120
    Summary
    Predicted to be involved in mitochondrial outer membrane permeabilization and positive regulation of programmed cell death. Predicted to act upstream of or within positive regulation of apoptotic process. Predicted to be located in membrane and mitochondrial envelope. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum; mitochondrial outer membrane; and nuclear envelope. Is expressed in axis; notochord; and polster. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    Location:
    chromosome: 17
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (20231817..20236284, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (20211981..20216448, complement)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene O-6-methylguanine-DNA methyltransferase Neighboring gene EBF transcription factor 3b Neighboring gene survival motor neuron domain containing 1 Neighboring gene adducin 3 (gamma) b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Clone Names

    • MGC123120

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables identical protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in mitochondrial outer membrane permeabilization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within positive regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of programmed cell death IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial envelope IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in mitochondrial outer membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nuclear envelope IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    BCL2 interacting protein 4
    Names
    BCL2/adenovirus E1B 19kDa interacting protein 3b
    BCL2/adenovirus E1B interacting protein 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_212693.2NP_997858.2  BCL2 interacting protein 4

      Status: VALIDATED

      Source sequence(s)
      BC108082, BX005375, EB966413
      UniProtKB/TrEMBL
      A0A8M1PHK5, F1QZM4, Q32PK3
      Related
      ENSDARP00000032168.8, ENSDART00000029380.10
      Conserved Domains (1) summary
      pfam06553
      Location:2172
      BNIP3; BNIP3

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      20231817..20236284 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394981.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      214428..218898 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)