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    Ankrd61 ankyrin repeat domain 61 [ Mus musculus (house mouse) ]

    Gene ID: 66729, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Ankrd61provided by MGI
    Official Full Name
    ankyrin repeat domain 61provided by MGI
    Primary source
    MGI:MGI:1913979
    See related
    Ensembl:ENSMUSG00000029607 AllianceGenome:MGI:1913979
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4921520G13Rik
    Summary
    Predicted to enable DNA binding activity. Predicted to be located in nucleoplasm. Orthologous to human ANKRD61 (ankyrin repeat domain 61). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in testis adult (RPKM 65.4) and liver E14 (RPKM 0.8) See more
    Orthologs
    human all
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    Genomic context

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    Location:
    5 G2; 5 82.79 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (143827455..143831885, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (143890637..143895067, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase 42 Neighboring gene predicted gene, 38737 Neighboring gene RIKEN cDNA D130017N08 gene Neighboring gene STARR-positive B cell enhancer ABC_E10364 Neighboring gene STARR-positive B cell enhancer ABC_E2182 Neighboring gene eukaryotic translation initiation factor 2 alpha kinase 1 Neighboring gene STARR-positive B cell enhancer ABC_E858 Neighboring gene aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 Neighboring gene PMS1 homolog2, mismatch repair system component Neighboring gene CCZ1 vacuolar protein trafficking and biogenesis associated Neighboring gene predicted gene, 24311

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
    2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
    5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    ankyrin repeat domain-containing protein 61

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001310772.1 → NP_001297701.1  ankyrin repeat domain-containing protein 61 isoform 2

      See identical proteins and their annotated locations for NP_001297701.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate splice site in the 5' terminal exon and initiates translation at an alternate start codon compared to variant 1. The encoded isoform (2) has a shorter, distinct N-terminus compared to isoform 1.
      Source sequence(s)
      AK014929, BC052346
      Consensus CDS
      CCDS80460.1
      UniProtKB/TrEMBL
      D3YXD2
      Related
      ENSMUSP00000078571.6, ENSMUST00000079624.12
      Conserved Domains (4) summary
      cd00204
      Location:122 → 255
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:129 → 232
      Ank_2; Ankyrin repeats (3 copies)
      pfam13857
      Location:220 → 274
      Ank_5; Ankyrin repeats (many copies)
      sd00045
      Location:126 → 155
      ANK; ANK repeat [structural motif]

    2. NM_025732.4 → NP_080008.1  ankyrin repeat domain-containing protein 61 isoform 1

      See identical proteins and their annotated locations for NP_080008.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the shorter transcript and encodes the longer isoform (1).
      Source sequence(s)
      AK014929, BC052346
      Consensus CDS
      CCDS39373.1
      UniProtKB/Swiss-Prot
      Q80W77, Q9CQM6
      UniProtKB/TrEMBL
      D3YXD2
      Related
      ENSMUSP00000106345.3, ENSMUST00000110717.9
      Conserved Domains (4) summary
      cd00204
      Location:164 → 297
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:171 → 274
      Ank_2; Ankyrin repeats (3 copies)
      pfam13857
      Location:262 → 316
      Ank_5; Ankyrin repeats (many copies)
      sd00045
      Location:168 → 197
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      143827455..143831885 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006504859.5 → XP_006504922.1  ankyrin repeat domain-containing protein 61 isoform X1

      UniProtKB/TrEMBL
      D3YXD2
      Conserved Domains (3) summary
      COG0666
      Location:148 → 275
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      sd00045
      Location:54 → 83
      ANK; ANK repeat [structural motif]
      cl39094
      Location:36 → 210
      Ank_2; Ankyrin repeats (3 copies)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9CQM6.1 GenPept UniProtKB/Swiss-Prot:Q9CQM6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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