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    CASR calcium sensing receptor [ Gallus gallus (chicken) ]

    Gene ID: 418266, updated on 5-Mar-2024

    Summary

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    Symbol
    CASRprovided by CGNC
    Full Name
    calcium sensing receptorprovided by CGNC
    Primary source
    CGNC:50721
    See related
    Ensembl:ENSGALG00010021732
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (76636030..76714066)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (76836106..76913998)

    Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene mannosidase alpha class 1A member 2 Neighboring gene CD86 molecule Neighboring gene cystatin B Neighboring gene cystatin A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Oral expressions and functional analyses of the extracellular calcium-sensing receptor (CaSR) in chicken. Omori H, et al. Sci Rep, 2022 Oct 22. PMID 36273034, Free PMC Article
    2. Tetramethylpyrazine inhibited hypoxia-induced expression of calcium-sensing receptors in pulmonary artery smooth muscle cells in chickens. Zhang H, et al. J Biol Regul Homeost Agents, 2018 May-Jun. PMID 29921373
    3. The origin of the parathyroid gland. Okabe M, et al. Proc Natl Acad Sci U S A, 2004 Dec 21. PMID 15591343, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in detection of calcium ion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular calcium ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of calcium ion transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    extracellular calcium-sensing receptor
    Names
    calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism)
    parathyroid cell calcium-sensing receptor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      76636030..76714066
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_416491.8 → XP_416491.6  extracellular calcium-sensing receptor

      UniProtKB/TrEMBL
      A0A8I3AZV5, A0A8V0ZLX2
      Related
      ENSGALP00010031719.1, ENSGALT00010052813.1
      Conserved Domains (2) summary
      cd15282
      Location:610 → 861
      7tmC_CaSR; calcium-sensing receptor, member of the class C of seven-transmembrane G protein-coupled receptors
      cd06364
      Location:33 → 529
      PBP1_CaSR; ligand-binding domain of the CaSR calcium-sensing receptor, a member of the family C receptors within the G-protein coupled receptor superfamily

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      76836106..76913998
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040661543.2 → XP_040517477.1  extracellular calcium-sensing receptor

      UniProtKB/TrEMBL
      A0A8I3AZV5, A0A8V0ZLX2
      Conserved Domains (2) summary
      cd15282
      Location:610 → 861
      7tmC_CaSR; calcium-sensing receptor, member of the class C of seven-transmembrane G protein-coupled receptors
      cd06364
      Location:33 → 529
      PBP1_CaSR; ligand-binding domain of the CaSR calcium-sensing receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
    Nucleotide Protein
    Heading Accession and Version

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