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    USP25 ubiquitin specific peptidase 25 [ Homo sapiens (human) ]

    Gene ID: 29761, updated on 22-Apr-2024

    Summary

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    Official Symbol
    USP25provided by HGNC
    Official Full Name
    ubiquitin specific peptidase 25provided by HGNC
    Primary source
    HGNC:HGNC:12624
    See related
    Ensembl:ENSG00000155313 MIM:604736; AllianceGenome:HGNC:12624
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    USP21
    Summary
    Ubiquitin (MIM 191339) is a highly conserved 76-amino acid protein involved in regulation of intracellular protein breakdown, cell cycle regulation, and stress response. Ubiquitin is released from degraded proteins by disassembly of the polyubiquitin chains, which is mediated by ubiquitin-specific proteases (USPs), such as USP25 (Valero et al., 1999 [PubMed 10644437]).[supplied by OMIM, Mar 2008]
    Expression
    Ubiquitous expression in testis (RPKM 20.1), endometrium (RPKM 11.0) and 25 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    Location:
    21q21.1
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 21 NC_000021.9 (15729982..15880064)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 21 NC_060945.1 (14085398..14235467)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 21 NC_000021.8 (17102301..17252383)

    Chromosome 21 - NC_000021.9Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U13 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13219 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:17114626-17115270 Neighboring gene RAD23B pseudogene 3 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr21:17125262-17125887 Neighboring gene RNA binding protein with multiple splicing-like pseudogene Neighboring gene Sharpr-MPRA regulatory region 15533 Neighboring gene NANOG hESC enhancer GRCh37_chr21:17357279-17357780 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr21:17364583-17365782 Neighboring gene RNA, U6 small nuclear 426, pseudogene Neighboring gene mir-99a-let-7c cluster host gene Neighboring gene VDAC2 pseudogene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. USP25 contributes to defective neurogenesis and cognitive impairments. Cai F, et al. FASEB J, 2023 Jun. PMID 37171286
    2. The deubiquitinase USP25 supports colonic inflammation and bacterial infection and promotes colorectal cancer. Wang XM, et al. Nat Cancer, 2020 Aug. PMID 35122046
    3. A quaternary tetramer assembly inhibits the deubiquitinating activity of USP25. Liu B, et al. Nat Commun, 2018 Nov 26. PMID 30478318, Free PMC Article
    4. Parkinson's Disease Genetic Loci in Rapid Eye Movement Sleep Behavior Disorder. Gan-Or Z, et al. J Mol Neurosci, 2015 Jul. PMID 25929833
    5. The UBA-UIM domains of the USP25 regulate the enzyme ubiquitination state and modulate substrate recognition. Denuc A, et al. PLoS One, 2009. PMID 19440361, Free PMC Article

    See all (89) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Expression of USP25 associates with fibrosis, inflammation and metabolism changes in IgG4-related disease.
      Title: Expression of USP25 associates with fibrosis, inflammation and metabolism changes in IgG4-related disease.
    2. Usp25-Erlin1/2 activity limits cholesterol flux to restrict virus infection.
      Title: Usp25-Erlin1/2 activity limits cholesterol flux to restrict virus infection.
    3. USP25 promotes hepatocellular carcinoma progression by interacting with TRIM21 via the Wnt/beta-catenin signaling pathway.
      Title: USP25 promotes hepatocellular carcinoma progression by interacting with TRIM21 via the Wnt/β-catenin signaling pathway.
    4. USP25 inhibits renal fibrosis by regulating TGFbeta-SMAD signaling pathway in Ang II-induced hypertensive mice.
      Title: USP25 inhibits renal fibrosis by regulating TGFβ-SMAD signaling pathway in Ang II-induced hypertensive mice.
    5. USP25 contributes to defective neurogenesis and cognitive impairments.
      Title: USP25 contributes to defective neurogenesis and cognitive impairments.
    6. Regulation of USP25 by SP1 Associates with Amyloidogenesis.
      Title: Regulation of USP25 by SP1 Associates with Amyloidogenesis.
    7. USP25 UPREGULATION BOOSTS GSDMD -MEDIATED PYROPTOSIS OF ACINAR CELLS IN ACUTE PANCREATITIS.
      Title: USP25 UPREGULATION BOOSTS GSDMD -MEDIATED PYROPTOSIS OF ACINAR CELLS IN ACUTE PANCREATITIS.
    8. Downregulation of deubiquitinating enzyme USP25 promotes the development of allergic rhinitis by enhancing TSLP signaling in the nasal epithelium.
      Title: Downregulation of deubiquitinating enzyme USP25 promotes the development of allergic rhinitis by enhancing TSLP signaling in the nasal epithelium.
    9. Deubiquitination of TNKS1 Regulates Wnt/beta-Catenin to Affect the Expression of USP25 to Promote the Progression of Glioma.
      Title: Deubiquitination of TNKS1 Regulates Wnt/β-Catenin to Affect the Expression of USP25 to Promote the Progression of Glioma.
    10. The deubiquitinase USP25 supports colonic inflammation and bacterial infection and promotes colorectal cancer.
      Title: The deubiquitinase USP25 supports colonic inflammation and bacterial infection and promotes colorectal cancer.
    Submit: New GeneRIF Correction See all GeneRIFs (36)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Genome-wide association study of panic disorder in the Japanese population.
    EBI GWAS Catalog
    Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables ATPase binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables SUMO binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables SUMO binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables cysteine-type deubiquitinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables cysteine-type deubiquitinase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables cysteine-type deubiquitinase activity TAS
    Traceable Author Statement
    more info
    		  
    enables deubiquitinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables peptidase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables ubiquitin binding NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    enables ubiquitin protein ligase binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables ubiquitin-like protein peptidase activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of ERAD pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of interleukin-17-mediated signaling pathway IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in negative regulation of response to oxidative stress IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein K48-linked deubiquitination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein K63-linked deubiquitination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein deubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein deubiquitination IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein modification process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in proteolysis TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in regulation of protein stability IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		  
    located_in cytosol TAS
    Traceable Author Statement
    more info
    		  
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    ubiquitin carboxyl-terminal hydrolase 25
    Names
    USP on chromosome 21
    deubiquitinating enzyme 25
    ubiquitin thioesterase 25
    ubiquitin thiolesterase 25
    ubiquitin-specific processing protease 25
    NP_001269970.1
    NP_001269971.1
    NP_001339489.1
    NP_001339490.1
    NP_001375228.1
    NP_001375229.1
    NP_001375230.1
    NP_001375231.1
    NP_037528.3
    XP_005261006.1
    XP_011527831.1
    XP_011527837.1
    XP_047296701.1
    XP_047296702.1
    XP_047296703.1
    XP_047296704.1
    XP_047296705.1
    XP_047296706.1
    XP_047296707.1
    XP_054180413.1
    XP_054180414.1
    XP_054180415.1
    XP_054180416.1
    XP_054180417.1
    XP_054180418.1
    XP_054180419.1
    XP_054180420.1
    XP_054180421.1
    XP_054180422.1
    XP_054180423.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001283041.3 → NP_001269970.1  ubiquitin carboxyl-terminal hydrolase 25 isoform USP25m

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (USP25m).
      Source sequence(s)
      AJ010597, AJ010598, BC075792, BM149594, FJ763652
      Consensus CDS
      CCDS63336.1
      UniProtKB/Swiss-Prot
      Q9UHP3
      Related
      ENSP00000383044.2, ENST00000400183.7
      Conserved Domains (3) summary
      cd02665
      Location:170 → 655
      Peptidase_C19I; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cd14354
      Location:15 → 60
      UBA_UBP25; UBA domain found in ubiquitin carboxyl-terminal hydrolase 25 (UBP25) and similar proteins
      pfam00443
      Location:168 → 405
      UCH; Ubiquitin carboxyl-terminal hydrolase

    2. NM_001283042.3 → NP_001269971.1  ubiquitin carboxyl-terminal hydrolase 25 isoform USP25b

      See identical proteins and their annotated locations for NP_001269971.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1, resulting in an isoform (USP25b) that is shorter than isoform a.
      Source sequence(s)
      AF170562, AJ010597, AJ010598, BC075792, BM149594
      Consensus CDS
      CCDS63337.1
      UniProtKB/Swiss-Prot
      Q9UHP3
      Related
      ENSP00000285681.2, ENST00000285681.6
      Conserved Domains (3) summary
      cd02665
      Location:170 → 655
      Peptidase_C19I; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cd14354
      Location:15 → 60
      UBA_UBP25; UBA domain found in ubiquitin carboxyl-terminal hydrolase 25 (UBP25) and similar proteins
      pfam00443
      Location:168 → 405
      UCH; Ubiquitin carboxyl-terminal hydrolase

    3. NM_001352560.2 → NP_001339489.1  ubiquitin carboxyl-terminal hydrolase 25 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AJ010597, AJ010598, BM149594
      Conserved Domains (2) summary
      cd02665
      Location:37 → 434
      Peptidase_C19I; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cd20486
      Location:547 → 827
      USP25_C; carboxyl-terminal domain of ubiquitin-specific protease 25 (USP25)

    4. NM_001352561.2 → NP_001339490.1  ubiquitin carboxyl-terminal hydrolase 25 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AJ010597, AJ010598, BM149594
      UniProtKB/TrEMBL
      Q9HA22
      Conserved Domains (2) summary
      cl02553
      Location:163 → 251
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
      cd20486
      Location:364 → 644
      USP25_C; carboxyl-terminal domain of ubiquitin-specific protease 25 (USP25)

    5. NM_001388299.1 → NP_001375228.1  ubiquitin carboxyl-terminal hydrolase 25 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AJ010597, AJ010598
      Conserved Domains (2) summary
      cd02665
      Location:37 → 434
      Peptidase_C19I; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cd20486
      Location:547 → 827
      USP25_C; carboxyl-terminal domain of ubiquitin-specific protease 25 (USP25)

    6. NM_001388300.1 → NP_001375229.1  ubiquitin carboxyl-terminal hydrolase 25 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AJ010597, AJ010598
      UniProtKB/TrEMBL
      Q9HA22
      Conserved Domains (2) summary
      cl02553
      Location:163 → 251
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
      cd20486
      Location:364 → 644
      USP25_C; carboxyl-terminal domain of ubiquitin-specific protease 25 (USP25)

    7. NM_001388301.1 → NP_001375230.1  ubiquitin carboxyl-terminal hydrolase 25 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AJ010597, AJ010598
      UniProtKB/TrEMBL
      Q9HA22
      Conserved Domains (2) summary
      cl02553
      Location:163 → 251
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
      cd20486
      Location:364 → 644
      USP25_C; carboxyl-terminal domain of ubiquitin-specific protease 25 (USP25)

    8. NM_001388302.1 → NP_001375231.1  ubiquitin carboxyl-terminal hydrolase 25 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AJ010597, AJ010598
      UniProtKB/TrEMBL
      Q9HA22
      Conserved Domains (2) summary
      cl02553
      Location:163 → 251
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
      cd20486
      Location:361 → 641
      USP25_C; carboxyl-terminal domain of ubiquitin-specific protease 25 (USP25)

    9. NM_013396.6 → NP_037528.3  ubiquitin carboxyl-terminal hydrolase 25 isoform USP25a

      See identical proteins and their annotated locations for NP_037528.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks two alternate in-frame exons in the 3' coding region, compared to variant 1, resulting in an isoform (USP25a) that is shorter than isoform a.
      Source sequence(s)
      AJ010597, AJ010598, BC075792, BM149594
      Consensus CDS
      CCDS33515.1
      UniProtKB/Swiss-Prot
      C0LSZ0, Q6DHZ9, Q9H9W1, Q9UHP3
      Related
      ENSP00000285679.6, ENST00000285679.10
      Conserved Domains (3) summary
      cd02665
      Location:170 → 655
      Peptidase_C19I; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cd14354
      Location:15 → 60
      UBA_UBP25; UBA domain found in ubiquitin carboxyl-terminal hydrolase 25 (UBP25) and similar proteins
      cl02553
      Location:168 → 298
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000021.9 Reference GRCh38.p14 Primary Assembly

      Range
      15729982..15880064
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011529529.2 → XP_011527831.1  ubiquitin carboxyl-terminal hydrolase 25 isoform X1

      Conserved Domains (3) summary
      cd02665
      Location:170 → 655
      Peptidase_C19I; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cd14354
      Location:15 → 60
      UBA_UBP25; UBA domain found in ubiquitin carboxyl-terminal hydrolase 25 (UBP25) and similar proteins
      pfam00443
      Location:168 → 405
      UCH; Ubiquitin carboxyl-terminal hydrolase

    2. XM_047440749.1 → XP_047296705.1  ubiquitin carboxyl-terminal hydrolase 25 isoform X5

    3. XM_047440751.1 → XP_047296707.1  ubiquitin carboxyl-terminal hydrolase 25 isoform X7

    4. XM_011529535.3 → XP_011527837.1  ubiquitin carboxyl-terminal hydrolase 25 isoform X8

      Conserved Domains (4) summary
      cd02665
      Location:170 → 399
      Peptidase_C19I; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cd14354
      Location:15 → 60
      UBA_UBP25; UBA domain found in ubiquitin carboxyl-terminal hydrolase 25 (UBP25) and similar proteins
      cl02553
      Location:168 → 298
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
      pfam00443
      Location:168 → 405
      UCH; Ubiquitin carboxyl-terminal hydrolase

    5. XM_047440745.1 → XP_047296701.1  ubiquitin carboxyl-terminal hydrolase 25 isoform X2

    6. XM_047440746.1 → XP_047296702.1  ubiquitin carboxyl-terminal hydrolase 25 isoform X3

    7. XM_047440748.1 → XP_047296704.1  ubiquitin carboxyl-terminal hydrolase 25 isoform X4

    8. XM_047440747.1 → XP_047296703.1  ubiquitin carboxyl-terminal hydrolase 25 isoform X4

    9. XM_005260949.5 → XP_005261006.1  ubiquitin carboxyl-terminal hydrolase 25 isoform X6

      Conserved Domains (1) summary
      cl02553
      Location:163 → 251
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...

    10. XM_047440750.1 → XP_047296706.1  ubiquitin carboxyl-terminal hydrolase 25 isoform X6

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060945.1 Alternate T2T-CHM13v2.0

      Range
      14085398..14235467
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054324439.1 → XP_054180414.1  ubiquitin carboxyl-terminal hydrolase 25 isoform X1

    2. XM_054324444.1 → XP_054180419.1  ubiquitin carboxyl-terminal hydrolase 25 isoform X5

    3. XM_054324447.1 → XP_054180422.1  ubiquitin carboxyl-terminal hydrolase 25 isoform X7

    4. XM_054324448.1 → XP_054180423.1  ubiquitin carboxyl-terminal hydrolase 25 isoform X8

    5. XM_054324438.1 → XP_054180413.1  ubiquitin carboxyl-terminal hydrolase 25 isoform X9

    6. XM_054324440.1 → XP_054180415.1  ubiquitin carboxyl-terminal hydrolase 25 isoform X2

    7. XM_054324441.1 → XP_054180416.1  ubiquitin carboxyl-terminal hydrolase 25 isoform X3

    8. XM_054324443.1 → XP_054180418.1  ubiquitin carboxyl-terminal hydrolase 25 isoform X4

    9. XM_054324442.1 → XP_054180417.1  ubiquitin carboxyl-terminal hydrolase 25 isoform X4

    10. XM_054324446.1 → XP_054180421.1  ubiquitin carboxyl-terminal hydrolase 25 isoform X6

    11. XM_054324445.1 → XP_054180420.1  ubiquitin carboxyl-terminal hydrolase 25 isoform X6

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9UHP3.4 GenPept UniProtKB/Swiss-Prot:Q9UHP3

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