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Locally Advanced Bladder Carcinoma

MedGen UID:
1712399
•Concept ID:
C5238239
•
Neoplastic Process

Definition

A bladder carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocally Advanced Bladder Carcinoma

Professional guidelines

PubMed

Combined treatment approaches in regionally advanced bladder cancer.
Walther PJ
Urol Clin North Am 1992 Nov;19(4):761-74. PMID: 1441030

Recent clinical studies

Etiology

Efficacy of radical cystectomy plus adjuvant intraarterial chemotherapy with gemcitabine and cisplatin on locally advanced bladder cancer.
Jiang L, Zhang Z, Dong P, Li Y, Yao K, Liu Z, Han H, Qin Z, Yao M, Zhou F
Chin Med J (Engl) 2014;127(7):1249-54. PMID: 24709175
Radiotherapy with concurrent carbogen and nicotinamide in bladder carcinoma.
Hoskin PJ, Rojas AM, Bentzen SM, Saunders MI
J Clin Oncol 2010 Nov 20;28(33):4912-8. Epub 2010 Oct 18 doi: 10.1200/JCO.2010.28.4950. PMID: 20956620
Clinical outcome in patients with locally advanced bladder carcinoma treated with conservative multimodality therapy.
George L, Bladou F, Bardou VJ, Gravis G, Tallet A, Alzieu C, Serment G, Salem N
Urology 2004 Sep;64(3):488-93. doi: 10.1016/j.urology.2004.04.088. PMID: 15351577
Advanced bladder cancer (stages pT3b, pT4a, pN1 and pN2): improved survival after radical cystectomy and 3 adjuvant cycles of chemotherapy. Results of a controlled prospective study.
Stöckle M, Meyenburg W, Wellek S, Voges G, Gertenbach U, Thüroff JW, Huber C, Hohenfellner R
J Urol 1992 Aug;148(2 Pt 1):302-6; discussion 306-7. doi: 10.1016/s0022-5347(17)36578-3. PMID: 1635123
Presurgery chemotherapy (CT) in locally advanced bladder carcinoma: a feasible and possibly effective approach.
Veronesi A, Dal Bo V, Morassut S, Merlo A, Carmignani G, Lo Re G, Carbone A, Magri MD, Talamini R, Francini M
Med Oncol Tumor Pharmacother 1989;6(2):179-82. doi: 10.1007/BF02985243. PMID: 2747309

Diagnosis

Bladder carcinoma during pregnancy.
Spahn M, Bader P, Westermann D, Echtle D, Frohneberg D
Urol Int 2005;74(2):153-9. doi: 10.1159/000083287. PMID: 15756068
Altered expression of retinoblastoma protein and known prognostic variables in locally advanced bladder cancer.
Logothetis CJ, Xu HJ, Ro JY, Hu SX, Sahin A, Ordonez N, Benedict WF
J Natl Cancer Inst 1992 Aug 19;84(16):1256-61. doi: 10.1093/jnci/84.16.1256. PMID: 1640485
Radical radiation treatment of invasive and locally advanced bladder carcinoma in elderly patients.
Smaaland R, Akslen LA, Tønder B, Mehus A, Lote K, Albrektsen G
Br J Urol 1991 Jan;67(1):61-9. doi: 10.1111/j.1464-410x.1991.tb15071.x. PMID: 1993278

Therapy

Neoadjuvant and adjuvant chemotherapy for locally advanced bladder carcinoma: development of novel bladder preservation approach, Osaka Medical College regimen.
Azuma H, Inamoto T, Takahara K, Ibuki N, Nomi H, Yamamoto K, Narumi Y, Ubai T
Int J Urol 2012 Jan;19(1):26-38. Epub 2011 Nov 13 doi: 10.1111/j.1442-2042.2011.02856.x. PMID: 22077821
Radiotherapy with concurrent carbogen and nicotinamide in bladder carcinoma.
Hoskin PJ, Rojas AM, Bentzen SM, Saunders MI
J Clin Oncol 2010 Nov 20;28(33):4912-8. Epub 2010 Oct 18 doi: 10.1200/JCO.2010.28.4950. PMID: 20956620
Carbogen and nicotinamide in locally advanced bladder cancer: early results of a phase-III randomized trial.
Hoskin PJ, Rojas AM, Saunders MI, Bentzen SM, Motohashi KJ; BCON investigators
Radiother Oncol 2009 Apr;91(1):120-5. Epub 2008 Nov 5 doi: 10.1016/j.radonc.2008.10.001. PMID: 18992952
Clinical outcome in patients with locally advanced bladder carcinoma treated with conservative multimodality therapy.
George L, Bladou F, Bardou VJ, Gravis G, Tallet A, Alzieu C, Serment G, Salem N
Urology 2004 Sep;64(3):488-93. doi: 10.1016/j.urology.2004.04.088. PMID: 15351577
Chemoradiotherapy in locally advanced bladder carcinoma.
Loehrer PJ Sr
Semin Oncol 1992 Aug;19(4 Suppl 11):92-5. PMID: 1509286

Prognosis

Bladder carcinoma during pregnancy.
Spahn M, Bader P, Westermann D, Echtle D, Frohneberg D
Urol Int 2005;74(2):153-9. doi: 10.1159/000083287. PMID: 15756068
Clinical outcome in patients with locally advanced bladder carcinoma treated with conservative multimodality therapy.
George L, Bladou F, Bardou VJ, Gravis G, Tallet A, Alzieu C, Serment G, Salem N
Urology 2004 Sep;64(3):488-93. doi: 10.1016/j.urology.2004.04.088. PMID: 15351577
Advanced bladder cancer (stages pT3b, pT4a, pN1 and pN2): improved survival after radical cystectomy and 3 adjuvant cycles of chemotherapy. Results of a controlled prospective study.
Stöckle M, Meyenburg W, Wellek S, Voges G, Gertenbach U, Thüroff JW, Huber C, Hohenfellner R
J Urol 1992 Aug;148(2 Pt 1):302-6; discussion 306-7. doi: 10.1016/s0022-5347(17)36578-3. PMID: 1635123
Radical radiation treatment of invasive and locally advanced bladder carcinoma in elderly patients.
Smaaland R, Akslen LA, Tønder B, Mehus A, Lote K, Albrektsen G
Br J Urol 1991 Jan;67(1):61-9. doi: 10.1111/j.1464-410x.1991.tb15071.x. PMID: 1993278
Presurgery chemotherapy (CT) in locally advanced bladder carcinoma: a feasible and possibly effective approach.
Veronesi A, Dal Bo V, Morassut S, Merlo A, Carmignani G, Lo Re G, Carbone A, Magri MD, Talamini R, Francini M
Med Oncol Tumor Pharmacother 1989;6(2):179-82. doi: 10.1007/BF02985243. PMID: 2747309

Clinical prediction guides

Tumor mapping of regional immunostaining for p21, p53, and mdm2 in locally advanced bladder carcinoma.
Jahnson S, Karlsson MG
Cancer 2000 Aug 1;89(3):619-29. PMID: 10931462
Feasibility, toxicity, and preliminary results of weekly loco-regional hyperthermia and cisplatin in patients with previously irradiated recurrent cervical carcinoma or locally advanced bladder cancer.
Rietbroek RC, Bakker PJ, Schilthuis MS, Postma AJ, Zum Vörde Sive Vording PJ, Gonzalèz Gonzalèz D, Kurth KH, Bakker AJ, Veenhof CH
Int J Radiat Oncol Biol Phys 1996 Mar 1;34(4):887-93. doi: 10.1016/0360-3016(95)02152-3. PMID: 8598366
Altered expression of retinoblastoma protein and known prognostic variables in locally advanced bladder cancer.
Logothetis CJ, Xu HJ, Ro JY, Hu SX, Sahin A, Ordonez N, Benedict WF
J Natl Cancer Inst 1992 Aug 19;84(16):1256-61. doi: 10.1093/jnci/84.16.1256. PMID: 1640485
Radical radiation treatment of invasive and locally advanced bladder carcinoma in elderly patients.
Smaaland R, Akslen LA, Tønder B, Mehus A, Lote K, Albrektsen G
Br J Urol 1991 Jan;67(1):61-9. doi: 10.1111/j.1464-410x.1991.tb15071.x. PMID: 1993278

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