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Central nervous system non-hodgkin lymphoma

MedGen UID:
745669
•Concept ID:
C2213246
•
Neoplastic Process
Synonyms: Central Nervous System Non-Hodgkin Lymphoma; central nervous system non-hodgkin lymphoma; Central nervous system non-Hodgkin lymphoma; central nervous system non-Hodgkin lymphoma; Non-Hodgkin lymphoma of central nervous system; non-Hodgkin lymphoma of central nervous system; Non-Hodgkin's lymphoma of central nervous system; Primary Central Nervous System Non-Hodgkin Lymphoma; Primary Central nervous system non-Hodgkin lymphoma
SNOMED CT: Non-Hodgkin lymphoma of central nervous system (448254007); Non-Hodgkin's lymphoma of central nervous system (448254007)
 
Monarch Initiative: MONDO:0044887

Definition

A non-Hodgkin lymphoma that arises from the central nervous system. [from NCI]

Professional guidelines

PubMed

Central Nervous System Lymphoma: Approach to Diagnosis and Treatment.
Correia CE, Schaff LR, Grommes C
Cancer J 2020 May/Jun;26(3):241-252. doi: 10.1097/PPO.0000000000000449. PMID: 32496457

Recent clinical studies

Etiology

Concomitant systemic and central nervous system non-Hodgkin lymphoma: the role of consolidation in terms of high dose therapy and autologous stem cell transplantation. A 60-case retrospective study from LYSA and the LOC network.
Damaj G, Ivanoff S, Coso D, Ysaebert L, Choquet S, Houillier C, Parcelier A, Abarah W, Marjanovic Z, Gressin R, Garidi R, Diouf M, Gac AC, Dupuis J, Troussard X, Morschhauseur F, Ghesquières H, Soussain C; LYSA and LOC network, France
Haematologica 2015 Sep;100(9):1199-206. Epub 2015 Jul 16 doi: 10.3324/haematol.2015.126110. PMID: 26185174Free PMC Article
Autologous stem cell transplantation with thiotepa, busulfan, and cyclophosphamide (TBC) conditioning in patients with CNS involvement by non-Hodgkin lymphoma.
Cote GM, Hochberg EP, Muzikansky A, Hochberg FH, Drappatz J, McAfee SL, Batchelor TT, LaCasce AS, Fisher DC, Abramson JS, Armand P, Chen YB
Biol Blood Marrow Transplant 2012 Jan;18(1):76-83. Epub 2011 Jul 13 doi: 10.1016/j.bbmt.2011.07.006. PMID: 21749848
Underestimation of relative risks by standardized incidence ratios for AIDS-related cancers.
Chaturvedi AK, Mbulaiteye SM, Engels EA
Ann Epidemiol 2008 Mar;18(3):230-4. doi: 10.1016/j.annepidem.2007.10.005. PMID: 18083545
AIDS-related cancer and severity of immunosuppression in persons with AIDS.
Biggar RJ, Chaturvedi AK, Goedert JJ, Engels EA; HIV/AIDS Cancer Match Study
J Natl Cancer Inst 2007 Jun 20;99(12):962-72. Epub 2007 Jun 12 doi: 10.1093/jnci/djm010. PMID: 17565153
The continuing increase in the incidence of primary central nervous system non-Hodgkin lymphoma: a surveillance, epidemiology, and end results analysis.
Olson JE, Janney CA, Rao RD, Cerhan JR, Kurtin PJ, Schiff D, Kaplan RS, O'Neill BP
Cancer 2002 Oct 1;95(7):1504-10. doi: 10.1002/cncr.10851. PMID: 12237919

Diagnosis

Concomitant systemic and central nervous system non-Hodgkin lymphoma: the role of consolidation in terms of high dose therapy and autologous stem cell transplantation. A 60-case retrospective study from LYSA and the LOC network.
Damaj G, Ivanoff S, Coso D, Ysaebert L, Choquet S, Houillier C, Parcelier A, Abarah W, Marjanovic Z, Gressin R, Garidi R, Diouf M, Gac AC, Dupuis J, Troussard X, Morschhauseur F, Ghesquières H, Soussain C; LYSA and LOC network, France
Haematologica 2015 Sep;100(9):1199-206. Epub 2015 Jul 16 doi: 10.3324/haematol.2015.126110. PMID: 26185174Free PMC Article
Atypical presentation of primary central nervous system non-Hodgkin lymphoma in immunocompetent young adults.
Cheatle JT, Aizenberg MR, Weinberg JS, Surdell DL
World Neurosurg 2013 Mar-Apr;79(3-4):593.e9-13. Epub 2012 Aug 7 doi: 10.1016/j.wneu.2012.07.026. PMID: 22885166
The continuing increase in the incidence of primary central nervous system non-Hodgkin lymphoma: a surveillance, epidemiology, and end results analysis.
Olson JE, Janney CA, Rao RD, Cerhan JR, Kurtin PJ, Schiff D, Kaplan RS, O'Neill BP
Cancer 2002 Oct 1;95(7):1504-10. doi: 10.1002/cncr.10851. PMID: 12237919
Proton MRS similarity between central nervous system non-Hodgkin lymphoma and intracranial tuberculoma.
Jayasundar R, Raghunathan P, Banerji AK
Magn Reson Imaging 1995;13(3):489-93. doi: 10.1016/0730-725x(94)00134-o. PMID: 7791559

Therapy

Concomitant systemic and central nervous system non-Hodgkin lymphoma: the role of consolidation in terms of high dose therapy and autologous stem cell transplantation. A 60-case retrospective study from LYSA and the LOC network.
Damaj G, Ivanoff S, Coso D, Ysaebert L, Choquet S, Houillier C, Parcelier A, Abarah W, Marjanovic Z, Gressin R, Garidi R, Diouf M, Gac AC, Dupuis J, Troussard X, Morschhauseur F, Ghesquières H, Soussain C; LYSA and LOC network, France
Haematologica 2015 Sep;100(9):1199-206. Epub 2015 Jul 16 doi: 10.3324/haematol.2015.126110. PMID: 26185174Free PMC Article
Atypical presentation of primary central nervous system non-Hodgkin lymphoma in immunocompetent young adults.
Cheatle JT, Aizenberg MR, Weinberg JS, Surdell DL
World Neurosurg 2013 Mar-Apr;79(3-4):593.e9-13. Epub 2012 Aug 7 doi: 10.1016/j.wneu.2012.07.026. PMID: 22885166
Autologous stem cell transplantation with thiotepa, busulfan, and cyclophosphamide (TBC) conditioning in patients with CNS involvement by non-Hodgkin lymphoma.
Cote GM, Hochberg EP, Muzikansky A, Hochberg FH, Drappatz J, McAfee SL, Batchelor TT, LaCasce AS, Fisher DC, Abramson JS, Armand P, Chen YB
Biol Blood Marrow Transplant 2012 Jan;18(1):76-83. Epub 2011 Jul 13 doi: 10.1016/j.bbmt.2011.07.006. PMID: 21749848

Prognosis

Concomitant systemic and central nervous system non-Hodgkin lymphoma: the role of consolidation in terms of high dose therapy and autologous stem cell transplantation. A 60-case retrospective study from LYSA and the LOC network.
Damaj G, Ivanoff S, Coso D, Ysaebert L, Choquet S, Houillier C, Parcelier A, Abarah W, Marjanovic Z, Gressin R, Garidi R, Diouf M, Gac AC, Dupuis J, Troussard X, Morschhauseur F, Ghesquières H, Soussain C; LYSA and LOC network, France
Haematologica 2015 Sep;100(9):1199-206. Epub 2015 Jul 16 doi: 10.3324/haematol.2015.126110. PMID: 26185174Free PMC Article
Atypical presentation of primary central nervous system non-Hodgkin lymphoma in immunocompetent young adults.
Cheatle JT, Aizenberg MR, Weinberg JS, Surdell DL
World Neurosurg 2013 Mar-Apr;79(3-4):593.e9-13. Epub 2012 Aug 7 doi: 10.1016/j.wneu.2012.07.026. PMID: 22885166
Autologous stem cell transplantation with thiotepa, busulfan, and cyclophosphamide (TBC) conditioning in patients with CNS involvement by non-Hodgkin lymphoma.
Cote GM, Hochberg EP, Muzikansky A, Hochberg FH, Drappatz J, McAfee SL, Batchelor TT, LaCasce AS, Fisher DC, Abramson JS, Armand P, Chen YB
Biol Blood Marrow Transplant 2012 Jan;18(1):76-83. Epub 2011 Jul 13 doi: 10.1016/j.bbmt.2011.07.006. PMID: 21749848
Underestimation of relative risks by standardized incidence ratios for AIDS-related cancers.
Chaturvedi AK, Mbulaiteye SM, Engels EA
Ann Epidemiol 2008 Mar;18(3):230-4. doi: 10.1016/j.annepidem.2007.10.005. PMID: 18083545
The continuing increase in the incidence of primary central nervous system non-Hodgkin lymphoma: a surveillance, epidemiology, and end results analysis.
Olson JE, Janney CA, Rao RD, Cerhan JR, Kurtin PJ, Schiff D, Kaplan RS, O'Neill BP
Cancer 2002 Oct 1;95(7):1504-10. doi: 10.1002/cncr.10851. PMID: 12237919

Clinical prediction guides

AIDS-related cancer and severity of immunosuppression in persons with AIDS.
Biggar RJ, Chaturvedi AK, Goedert JJ, Engels EA; HIV/AIDS Cancer Match Study
J Natl Cancer Inst 2007 Jun 20;99(12):962-72. Epub 2007 Jun 12 doi: 10.1093/jnci/djm010. PMID: 17565153
The continuing increase in the incidence of primary central nervous system non-Hodgkin lymphoma: a surveillance, epidemiology, and end results analysis.
Olson JE, Janney CA, Rao RD, Cerhan JR, Kurtin PJ, Schiff D, Kaplan RS, O'Neill BP
Cancer 2002 Oct 1;95(7):1504-10. doi: 10.1002/cncr.10851. PMID: 12237919
Proton MRS similarity between central nervous system non-Hodgkin lymphoma and intracranial tuberculoma.
Jayasundar R, Raghunathan P, Banerji AK
Magn Reson Imaging 1995;13(3):489-93. doi: 10.1016/0730-725x(94)00134-o. PMID: 7791559

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