| | Single nucleotide polymorphisms (SNPs) are identified by comparing high |
| | quality genomic sequence data from overlapping large-insert clones such as |
| | bacterial artificial chromosomes (BACs) or P1-based artificial chromosomes |
| | (PACs). An STS containing this SNP is then developed and the existence of |
| | the SNP in various populations is confirmed by pooled DNA sequencing (see |
| | Taillon-Miller et al. (1998) Overlapping Genomic Sequences: A Treasure |
| | Trove of Single Nucleotide Polymorphisms Genome Research, in press). |
