DNA methylation inhibitor effect on melanoma cell lines
Summary:
Analysis of six melanoma cell lines treated with the DNA methylation inhibitor 5-aza-2'-deoxycytidine (5AzadC). Results provide insight into the role of epigenetic silencing by DNA methylation in the pathogenesis of melanoma.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Muthusamy V, Duraisamy S, Bradbury CM, Hobbs C et al. Epigenetic silencing of novel tumor suppressors in malignant melanoma. Cancer Res 2006 Dec 1;66(23):11187-93. PMID: 17145863