Preinvasive and invasive cervical squamous cell carcinomas
Summary:
Analysis of LCM-harvested high-grade squamous intraepithelial lesions (HSIL) and invasive squamous cell carcinomas (SCC) from cervices. If left untreated, a subset of the HSILs will progress to SCCs. Results provide insight into the molecular mechanisms underlying cervical cancer progression.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Zhai Y, Kuick R, Nan B, Ota I et al. Gene expression analysis of preinvasive and invasive cervical squamous cell carcinomas identifies HOXC10 as a key mediator of invasion. Cancer Res 2007 Nov 1;67(21):10163-72. PMID: 17974957