Ileocecal epithelial cell line response to Clostridium difficile toxins A and B: time course
Summary:
Analysis of HCT-8 ileocecal cells treated with Clostridium difficile toxin A or B for up to 24 hours. C. difficile, a gram-positive, spore-forming anaerobe, causes infections leading to pseudomembranous colitis. Results provide insight into the role of toxins A and B in C. difficile infections.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
D'Auria KM, Donato GM, Gray MC, Kolling GL et al. Systems analysis of the transcriptional response of human ileocecal epithelial cells to Clostridium difficile toxins and effects on cell cycle control. BMC Syst Biol 2012 Jan 6;6:2. PMID: 22225989
