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    cyp17 cytochrome P-450 17alpha-hydroxylase/C17,20-lyase [ Oryzias latipes (Japanese medaka) ]

    Gene ID: 100125816, updated on 8-Mar-2024

    Summary

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    Gene symbol
    cyp17
    Gene description
    cytochrome P-450 17alpha-hydroxylase/C17,20-lyase
    See related
    EnsemblRapid:ENSORLG00000019226
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Oryzias latipes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae; Oryzias
    Also known as
    CYP17A1
    Orthologs
    human zebrafish all
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    Genomic context

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    See cyp17 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    103 current ASM223467v1 (GCF_002234675.1) 15 NC_019873.2 (1614752..1622451, complement)
    102 previous assembly ASM31367v1 (GCF_000313675.1) Unplaced Scaffold NW_004089500.1 (180212..187836, complement)

    Chromosome 15 - NC_019873.2Genomic Context describing neighboring genes Neighboring gene cyclin-dependent kinase 1 Neighboring gene cytosolic thiouridylase subunit 2 homolog (S. pombe) Neighboring gene ring finger protein 166 Neighboring gene pre-mRNA-processing ATP-dependent RNA helicase prp5 Neighboring gene BLOC-1 related complex subunit 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Isolation, characterization, and expression of cDNAs encoding the medaka (Oryzias latipes) ovarian follicle cytochrome P-450 aromatase. Fukada S, et al. Mol Reprod Dev, 1996 Nov. PMID 8916038
    2. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 17-alpha-hydroxyprogesterone aldolase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables steroid 17-alpha-monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in hormone biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in progesterone metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    steroid 17-alpha-hydroxylase/17,20 lyase
    Names
    17-alpha-hydroxyprogesterone aldolase
    CYPXVII
    cytochrome P450 17A1
    cytochrome P450-C17
    cytochrome P450c17
    NP_001098564.1
    XP_020555398.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105094.1 → NP_001098564.1  steroid 17-alpha-hydroxylase/17,20 lyase

      See identical proteins and their annotated locations for NP_001098564.1

      Status: PROVISIONAL

      Source sequence(s)
      D87121
      UniProtKB/Swiss-Prot
      P70085, P70086
      UniProtKB/TrEMBL
      H2MY89
      Related
      ENSORLP00000064399.1, ENSORLT00000061444.1
      Conserved Domains (1) summary
      pfam00067
      Location:34 → 501
      p450; Cytochrome P450

    RefSeqs of Annotated Genomes: Oryzias latipes Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM223467v1 Primary Assembly

    Genomic

    1. NC_019873.2 Reference ASM223467v1 Primary Assembly

      Range
      1614752..1622451 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_020699739.2 → XP_020555398.1  steroid 17-alpha-hydroxylase/17,20 lyase isoform X1

      Related
      ENSORLP00000088917.1, ENSORLT00000098770.1
      Conserved Domains (1) summary
      pfam00067
      Location:123 → 561
      p450; Cytochrome P450
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P70085.1 GenPept UniProtKB/Swiss-Prot:P70085

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials