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    Otc ornithine transcarbamylase [ Heterocephalus glaber (naked mole-rat) ]

    Gene ID: 101706852, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Otc
    Gene description
    ornithine transcarbamylase
    Locus tag
    GW7_05823
    See related
    Ensembl:ENSHGLG00000006935
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Heterocephalus glaber
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
    Orthologs
    human mouse all
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    Genomic context

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    See Otc in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624762.1 (17038223..17104853, complement)

    NW_004624762.1Genomic Context describing neighboring genes Neighboring gene zinc finger CCCH domain-containing protein 15 pseudogene Neighboring gene ferritin light chain pseudogene Neighboring gene retinitis pigmentosa GTPase regulator Neighboring gene 40S ribosomal protein S26

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_004624762 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Kim EB, et al. Nature, 2011 Oct 12. PMID 21993625, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables amino acid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ornithine carbamoyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in arginine biosynthetic process via ornithine IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in citrulline biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ornithine carbamoyltransferase, mitochondrial
    Names
    Ornithine carbamoyltransferase, mitochondrial

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference HetGla_female_1.0 Primary Assembly

    Genomic

    1. NW_004624762.1 Reference HetGla_female_1.0 Primary Assembly

      Range
      17038223..17104853 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004850027.3 → XP_004850084.1  ornithine carbamoyltransferase, mitochondrial

      See identical proteins and their annotated locations for XP_004850084.1

      UniProtKB/TrEMBL
      G5BMQ9
      Related
      ENSHGLP00000009666.1, ENSHGLT00000009773.1
      Conserved Domains (3) summary
      PRK00779
      Location:36 → 342
      PRK00779; ornithine carbamoyltransferase; Provisional
      pfam00185
      Location:188 → 341
      OTCace; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
      pfam02729
      Location:41 → 181
      OTCace_N; Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
    Nucleotide Protein
    Heading Accession and Version

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