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    MYO1A myosin IA [ Bos taurus (cattle) ]

    Gene ID: 281936, updated on 5-Mar-2024

    Summary

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    Official Symbol
    MYO1Aprovided by VGNC
    Official Full Name
    myosin IAprovided by VGNC
    Primary source
    VGNC:VGNC:31816
    See related
    BGD:BT19391; Ensembl:ENSBTAG00000014655
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See MYO1A in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (56377071..56406135)

    Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene glycine cleavage system protein H pseudogene Neighboring gene nuclear envelope integral membrane protein 1 Neighboring gene tachykinin precursor 3 Neighboring gene zinc finger and BTB domain containing 39

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of a new type of mammalian myosin heavy chain by molecular cloning. Overlap of its mRNA with preprotachykinin B mRNA. Hoshimaru M, et al. J Biol Chem, 1987 Oct 25. PMID 3667594
    2. Structural organization and expression of the gene for bovine myosin I heavy chain. Kawakami H, et al. J Biochem, 1992 Mar. PMID 1587791
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC127048

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables microfilament motor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin filament organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sensory perception of sound IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in vesicle transport along actin filament IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in brush border IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in microvillus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of myosin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in vesicle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    unconventional myosin-Ia
    Names
    BBM-I
    BBMI
    MIHC
    brush border 110 kDa protein
    brush border myosin I
    myosin I heavy chain
    myosin-Ia

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174395.3 → NP_776820.1  unconventional myosin-Ia

      See identical proteins and their annotated locations for NP_776820.1

      Status: PROVISIONAL

      Source sequence(s)
      J02819
      UniProtKB/Swiss-Prot
      P10568, Q2KJJ6, Q9TS38
      Related
      ENSBTAP00000019518.5, ENSBTAT00000019518.6
      Conserved Domains (4) summary
      smart00015
      Location:742 → 764
      IQ; Calmodulin-binding motif
      cd01378
      Location:22 → 681
      MYSc_Myo1; class I myosin, motor domain
      pfam00063
      Location:10 → 681
      Myosin_head; Myosin head (motor domain)
      pfam06017
      Location:847 → 1018
      Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      56377071..56406135
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015471065.3 → XP_015326551.1  unconventional myosin-Ia isoform X1

      Conserved Domains (3) summary
      smart00015
      Location:753 → 775
      IQ; Calmodulin-binding motif
      cd01378
      Location:22 → 692
      MYSc_Myo1; class I myosin, motor domain
      pfam06017
      Location:858 → 1053
      Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding

    2. XM_005206510.5 → XP_005206567.1  unconventional myosin-Ia isoform X2

      See identical proteins and their annotated locations for XP_005206567.1

      UniProtKB/Swiss-Prot
      P10568, Q2KJJ6, Q9TS38
      Conserved Domains (4) summary
      smart00015
      Location:742 → 764
      IQ; Calmodulin-binding motif
      cd01378
      Location:22 → 681
      MYSc_Myo1; class I myosin, motor domain
      pfam00063
      Location:10 → 681
      Myosin_head; Myosin head (motor domain)
      pfam06017
      Location:847 → 1018
      Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P10568.1 GenPept UniProtKB/Swiss-Prot:P10568

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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    Research Materials