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    ar.L androgen receptor L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 399456, updated on 11-Apr-2024

    Summary

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    Official Symbol
    ar.L
    Official Full Name
    androgen receptor L homeolog
    Primary source
    Xenbase:XB-GENE-479433
    Locus tag
    XELAEV_18002878mg
    See related
    EnsemblRapid:ENSXLAG00005031532
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    ar; ADR; Xl alpha AR
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    Genomic context

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    See ar.L in Genome Data Viewer
    Location:
    chromosome: 8L
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8L NC_054385.1 (30541025..30689464, complement)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) Unplaced Scaffold NW_016694828.1 (812014..958903)

    Chromosome 8L - NC_054385.1Genomic Context describing neighboring genes Neighboring gene probable G-protein coupled receptor 83 Neighboring gene oligophrenin 1 L homeolog Neighboring gene Yip1 domain family member 6 L homeolog Neighboring gene uncharacterized LOC121396969 Neighboring gene ectodysplasin A2 receptor L homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An androgen receptor mRNA isoform associated with hormone-induced cell proliferation. Fischer L, et al. Proc Natl Acad Sci U S A, 1993 Sep 1. PMID 7690145, Free PMC Article
    2. Androgen-directed development of the Xenopus laevis larynx: control of androgen receptor expression and tissue differentiation. Fischer LM, et al. Dev Biol, 1995 Jul. PMID 7601302
    3. Identification of androgen receptor variants in testis from humans and other vertebrates. Laurentino SS, et al. Andrologia, 2013 Jun. PMID 22734680
    4. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. ARDelta2(Stop) was expressed in rat and gilthead seabream testis, while an ARDelta3 was detected in African clawed frog testis.
      Title: Identification of androgen receptor variants in testis from humans and other vertebrates.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables estrogen response element binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nuclear receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables steroid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within androgen receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within intracellular steroid hormone receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within male gonad development IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    androgen receptor; androgen receptor L homeolog
    Names
    androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease) L homeolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054385.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      30541025..30689464 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_041572639.1 → XP_041428573.1  androgen receptor

      UniProtKB/TrEMBL
      A0A8J1LG91, B7ZS00, P70048
      Related
      ENSXLAP00005094469.1, ENSXLAT00005096171.1
      Conserved Domains (3) summary
      cd07073
      Location:542 → 787
      NR_LBD_AR; Ligand binding domain of the nuclear receptor androgen receptor, ligand activated transcription regulator
      cd07173
      Location:423 → 504
      NR_DBD_AR; DNA-binding domain of androgen receptor (AR) is composed of two C4-type zinc fingers
      pfam02166
      Location:6 → 345
      Androgen_recep; Androgen receptor

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001090884.1: Suppressed sequence

      Description
      NM_001090884.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.
    Nucleotide Protein Strain
    Heading Accession and Version

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