|
| Status |
Public on Apr 28, 2009 |
| Title |
Expression data from human breast tumors and their paired normal tissues |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Microarray is widely used to monitor gene expression changes in breast cancer. The transcriptomic changes in breast cancer is commonly occured during the transition of normal cells to cancerous cells. This is the first study on gene expression profiling of multi ethnic of Malaysian breast cancer patients (Malays, Chinese and Indian). We aim to identify differentially expressed genes between tumors and normal tissues. We have identified a set of 33 significant differentially expressed genes in the tumor vs. normal group at p<0.001.
We study the gene expression patterns of 43 breast tumors and their paired normal control by using Affymetrix genechip U133A. We have identified a set of 33 significant differentially expressed genes in the tumor vs. normal group at p<0.001.
|
| |
|
| Overall design |
Total RNAs were extracted from breast cancer and normal tissues. Samples were processed and hybridized on the chip for 16 hours. At the end of the study, we obtained a total of 86 set of gene expression data, which were from 43 tumors and 43 normal tissues. The gene expression were then compared between the tumor and normal groups.
|
| |
|
| Contributor(s) |
Bong I, Ni P, Zakaria Z, Muhammad R, Abdullah N, Ibrahim N, Emran NA, Abdullah NH, Hussain SN |
| Citation(s) |
20097481 |
| Submission date |
Apr 27, 2009 |
| Last update date |
Aug 10, 2018 |
| Contact name |
Ivyna PN Bong |
| E-mail(s) |
ivyna@moh.gov.my
|
| Phone |
+603 26162715
|
| Organization name |
Institute for Medical Research
|
| Department |
Cancer Research Centre
|
| Lab |
Genetics
|
| Street address |
Jalan Pahang
|
| City |
Kuala Lumpur |
| State/province |
Kuala Lumpur |
| ZIP/Postal code |
50588 |
| Country |
Malaysia |
| |
|
| Platforms (1) |
| GPL96 |
[HG-U133A] Affymetrix Human Genome U133A Array |
|
| Samples (86)
|
|
| Relations |
| BioProject |
PRJNA116827 |
Less...
More...