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Select item 48591.

Prolactinoma

Analysis of prolactinomas and normal pituitary tissues. Prolactinoma is a benign pituitary tumor that produces excessive prolactin resulting in hyperprolactinemia. Results provide insight into molecular mechanisms underlying the pathogenesis of this pituitary condition.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 disease state sets

Platform:: GPL8300
Series:: GSE36314
7 Samples

Download data: CEL

DataSet

Accession:: GDS4859

ID:: 4859

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 43562.

Zaire ebolavirus infection of macrophage: time course

Analysis of primary macrophages from three donors (D1, D2, D3) up to 6 hrs after in vitro exposure to purified Zaire ebolavirus (ZEBOV) virions. ZEBOV is the etiological agent of Ebola Hemorrhagic Fever (EHF). Results provide insight into the initial response of macrophages exposed to Ebola virions.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 3 individual, 2 infection, 2 time sets

Platform:: GPL8300
Series:: GSE31747
12 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS4356

ID:: 4356

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 52083.

Dexamethasone effect on epidermal keratinocytes in vitro: time course

Analysis of cultured epidermal keratinocytes treated with the synthetic glucocorticoid (GC) dexamethasone for up to 72 hours. GCs are used as therapeutic agents for skin conditions. Results provide insight into the molecular response of the epidermis to GCs.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 agent, 5 time sets

Platform:: GPL8300
Series:: GSE26487
20 Samples

Download data: CEL

DataSet

Accession:: GDS5208

ID:: 5208

Select item 44174.

Inhaled corticotherapy effect on allergic asthma: bronchial biopsies

Analysis of bronchial biopsies from allergic asthma (AA) subjects following inhaled corticosteroids (ICS) therapy. ICS represent potent anti-inflammatory controller medications for the treatment of asthma. Results provide insight into molecular mechanisms underlying the pathophysiology of AA.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 3 agent, 2 disease state, 2 specimen sets

Platform:: GPL8300
Series:: GSE15823
12 Samples

Download data: CEL

DataSet

Accession:: GDS4417

ID:: 4417

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 35115.

HIV-1 infection effect on macrophages in vitro: time course

Analysis of cultured macrophages for up to 7 days after HIV-1 infection. Macrophages are targets of HIV-1 infection and constitute a viral reservoir that facilitates the spread of HIV-1 to other cells. Results provide insight into the signaling networks affected by HIV-1 infection in macrophages.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 infection, 3 time sets

Platform:: GPL8300
Series:: GSE13395
16 Samples

Download data: CEL

DataSet

Accession:: GDS3511

ID:: 3511

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 33456.

Various mental disorders: postmortem brains

Analysis of postmortem prefrontal cortices from subjects with bipolar disorder, depression, and schizophrenia. Results provide insight into the molecular pathophysiology of these mental disorders.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 4 disease state sets

Platform:: GPL8300
Series:: GSE12654
50 Samples

Download data: CEL

DataSet

Accession:: GDS3345

ID:: 3345

Select item 36817.

Type 2 diabetes: myotube

Analysis of myotube cell lines established from type 2 diabetes (T2D) subjects. Insulin resistance and reduced mitochondrial biogenesis coexist early in T2D pathogenesis independent of hyperglycemia and obesity. Results provide insight into the effect of T2D on developing skeletal muscle cells.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 disease state sets

Platform:: GPL8300
Series:: GSE12643
20 Samples

Download data: CEL

DataSet

Accession:: GDS3681

ID:: 3681

Select item 33848.

Cyclooxygenase-2 inhibitor celecoxib effect on colorectal adenocarcinoma

Analysis of colorectal adenocarcinomas resected from patients treated with celecoxib for 7 days. Celecoxib is a cycooxygenase-2 inibitor that exhibits anti-cancer activity. Results provide insight into the mechanism of action of celecoxib in vivo.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 agent sets

Platform:: GPL8300
Series:: GSE11237
23 Samples

Download data: CEL

DataSet

Accession:: GDS3384

ID:: 3384

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 32159.

13-cis retinoic acid effect on SEB-1 sebocyte cell line

Analysis of cultured sebaceous gland cells (SEB-1 sebocytes) treated with 13-cis retinoic acid (13-cis RA, isotretinoin), a potent acne treatment agent that reduces the size and secretion of sebaceous glands. Results provide insight into the molecular basis for 13-cis RA's acne-clearing effect.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 agent sets

Platform:: GPL8300
Series:: GSE10432
6 Samples

Download data: CEL

DataSet

Accession:: GDS3215

ID:: 3215

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 319210.

Rheumatoid arthritis: synovial macrophages

Analysis of synovial fluid macrophages from 5 patients with rheumatoid arthritis (RA). The chronic inflammation and progressive joint destruction observed in RA are mediated in part by macrophages. Results provide insight into the molecular mechanisms underlying RA pathogenesis.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 disease state sets

Platform:: GPL8300
Series:: GSE10500
8 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS3192

ID:: 3192

Select item 317511.

NF-kappaB and phosphotidylinositol 3-kinase inhibitor treated monocytes infected with the human cytomegalovirus

Analysis of monocytes treated with an NF-kappaB or a phosphatidylinositol 3-kinase (PI3K) inhibitor and then infected with the human cytomegalovirus (HCMV). Results provide insight into the role of NF-kappaB and PI3K in the activation of monocytes to a proinflammatory state after an HCMV infection.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 3 agent sets

Platform:: GPL8300
Series:: GSE9601
12 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS3175

ID:: 3175

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 293112.

Rheumatoid arthritis and osteoarthritis: synovial fibroblasts

Comparison of synovial fibroblasts from patients with rheumatoid arthritis (RA) to those with osteoarthritis (OA). RA is characterized by chronic inflammation and destruction of multiple joints. OA is a degenerative disease resulting from the breakdown of cartilage.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 other sets

Platform:: GPL8300
Series:: GSE7669
12 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS2931

ID:: 2931

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 285813.

Analysis of microvascular endothelial cells (ECs) treated with the myeloid-related protein 8 (MRP8) and 14 (MRP14), proteins that form heterodimers secreted by phagocytes at inflammatory sites. Results provide insight into the role of MRP8 and MRP14 in EC cell death during inflammation.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 agent sets

Platform:: GPL8300
Series:: GSE5474
8 Samples

Download data

DataSet

Accession:: GDS2858

ID:: 2858

Select item 284214.

Testicular seminoma progression

Analysis of testicular seminoma tumors at various stages of progression (pT1, pT2, pT3). Results provide insight into the pathogenesis of testicular seminoma.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 4 disease state sets

Platform:: GPL8300
Series:: GSE8607
43 Samples

Download data: CEL, CHP, EXP

DataSet

Accession:: GDS2842

ID:: 2842

Select item 278515.

Ovarian cancer tumors after neo-adjuvant chemotherapy

Analysis of malignant ovarian cancer tumors from patients receiving neo-adjuvant chemotherapy. Ovarian adenomas and untreated ovarian carcinomas also examined. Results used to define gene expression signatures associated with clinical responses to chemotherapy.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 disease state, 2 protocol sets

Platform:: GPL8300
Series:: GSE7463
43 Samples

Download data: CEL

DataSet

Accession:: GDS2785

ID:: 2785

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 267816.

Brain regions of humans and chimpanzees

Comparison of various human and chimpanzee brain regions. Results provide insight into the genetic basis of human specializations in brain organization and cognition.

Organism:: Pan troglodytes; Homo sapiens

Type:: Expression profiling by array, count, 2 species, 12 tissue sets

Platform:: GPL8300
Series:: GSE7540
37 Samples

Download data: CEL, CHP, EXP

DataSet

Accession:: GDS2678

ID:: 2678

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 300417.

Heat stress effect on an epithelial cell line

Analysis of HEp2 epithelial cells subjected to heat stress at temperatures of 37 to 40 degrees C. Results provide insight into the regulatory pathways that control the response to heat stress.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 5 temperature sets

Platform:: GPL8300
Series:: GSE7458
13 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS3004

ID:: 3004

Select item 260318.

Arsenite and p53 effect on G2 synchronized fibroblasts

Analysis of p53-expressing or p53-deficient fibroblasts exposed to arsenite (As) after release from G2 phase synchrony. p53 is activated in response to mitotic disruption by arsenic. Results provide insight into the role of p53 in the As-induced disruption of G2/M phase progression.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 agent, 2 protocol sets

Platform:: GPL8300
Series:: GSE7101
16 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS2603

ID:: 2603

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 264219.

Crohn's disease and ulcerative colitis

Analysis of colonoscopic biopsies from patients with Crohn’s disease (CD) or ulcerative colitis (UC). CD and UC are inflammatory bowel diseases with variable, overlapping clinical features and complex pathophysiologies. Results provide insight into the pathogenesis of CD and UC.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 5 disease state, 3 specimen sets

Platform:: GPL8300
Series:: GSE6731
36 Samples

Download data: CEL, EXP

DataSet

Accession:: GDS2642

ID:: 2642

Select item 272920.

Cyclophosphamide-resistant chronic myelogenous leukemia cell line

Analysis of chronic myelogenous leukemia (CML) cells resistant to cyclophosphamide (CP), an alkylating anticancer drug. Results provide insight into the molecular basis of CP resistance in CML.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 cell line sets

Platform:: GPL8300
Series:: GSE7114
10 Samples

Download data: CEL

DataSet

Accession:: GDS2729

ID:: 2729

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