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Items: 14

1.

Mesenchymal Stem Cells Reduce Inflammation while Enhancing Bacterial Clearance and Improving Survival in Sepsis

(Submitter supplied) Expression data from Total RNA extracted from murine spleen. Sepsis was induced in C57Bl/6J mice by cecal ligation and puncture (CLP), followed 6 hours later by an intravenous injection of Mesenchymal Stem Cell (MSC) or saline. Twenty-eight hours after CLP, plasma, bronchoalveolar lavage (BAL) fluid and tissues were collected for analyses. Total RNA was extracted using Trizol (as per manufactures' instruction) followed by clean-up procedure using Qiagen RNA easy Prep (as per manufactures instructions) In the following study we hypothesized that mesenchymal stem cells (MSCs), which have documented immunomodulatory properties, would reduce sepsis-associated inflammation and organ injury in a clinically relevant model of sepsis.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6887
12 Samples
Download data: TXT
Series
Accession:
GSE24357
ID:
200024357
2.

Illumina MouseWG-6 v2.0 expression beadchip

(Submitter supplied) The MouseWG-6 v2.0 Expression BeadChip offer the most up-to-date content for whole-genome expression profiling in the mouse. Featuring content derived from the National Center for Biotechnology Information Reference Sequence (NCBI RefSeq) database (Build 36, Release 22). Please use the GEO Data Submission Report Plug-in v1.0 for Gene Expression which may be downloaded from https://icom.illumina.com/icom/software.ilmn?id=234 to format the normalized and raw data. more...
Organism:
Mus musculus
31 DataSets
1215 Series
8 Related Platforms
17084 Samples
Download data: BGX, TXT
Platform
Accession:
GPL6887
ID:
100006887
3.

HTHY5 (sham/saline)

Organism:
Mus musculus
Source name:
Sham Surgery (control animals)
Platform:
GPL6887
Series:
GSE24357
Download data
Sample
Accession:
GSM600365
ID:
300600365
4.

HTHY4 (sham/saline)

Organism:
Mus musculus
Source name:
Sham Surgery (control animals)
Platform:
GPL6887
Series:
GSE24357
Download data
Sample
Accession:
GSM600364
ID:
300600364
5.

MSC8 (CLP/MSC)

Organism:
Mus musculus
Source name:
Cecal-Ligation-and-Puncture (CLP) Model of Sepsis + MSC administration
Platform:
GPL6887
Series:
GSE24357
Download data
Sample
Accession:
GSM600363
ID:
300600363
6.

MSC7 (CLP/MSC)

Organism:
Mus musculus
Source name:
Cecal-Ligation-and-Puncture (CLP) Model of Sepsis + MSC administration
Platform:
GPL6887
Series:
GSE24357
Download data
Sample
Accession:
GSM600362
ID:
300600362
7.

CLP10 (CLP/saline)

Organism:
Mus musculus
Source name:
Cecal-Ligation-and-Puncture (CLP) Model of Sepsis + saline administration
Platform:
GPL6887
Series:
GSE24357
Download data
Sample
Accession:
GSM600361
ID:
300600361
8.

CLP8 (CLP/saline)

Organism:
Mus musculus
Source name:
Cecal-Ligation-and-Puncture (CLP) Model of Sepsis + saline administration
Platform:
GPL6887
Series:
GSE24357
Download data
Sample
Accession:
GSM600360
ID:
300600360
9.

HTHY3 (sham/saline)

Organism:
Mus musculus
Source name:
Sham Surgery (control animals)
Platform:
GPL6887
Series:
GSE24357
Download data
Sample
Accession:
GSM600359
ID:
300600359
10.

HTHY1 (sham/saline)

Organism:
Mus musculus
Source name:
Sham Surgery (control animals)
Platform:
GPL6887
Series:
GSE24357
Download data
Sample
Accession:
GSM600358
ID:
300600358
11.

MSC5 (CLP/MSC)

Organism:
Mus musculus
Source name:
Cecal-Ligation-and-Puncture (CLP) Model of Sepsis + MSC administration
Platform:
GPL6887
Series:
GSE24357
Download data
Sample
Accession:
GSM600357
ID:
300600357
12.

MSC4 (CLP/MSC)

Organism:
Mus musculus
Source name:
Cecal-Ligation-and-Puncture (CLP) Model of Sepsis + MSC administration
Platform:
GPL6887
Series:
GSE24357
Download data
Sample
Accession:
GSM600356
ID:
300600356
13.

CLP3 (CLP/saline)

Organism:
Mus musculus
Source name:
Cecal-Ligation-and-Puncture (CLP) Model of Sepsis + saline administration
Platform:
GPL6887
Series:
GSE24357
Download data
Sample
Accession:
GSM600355
ID:
300600355
14.

CLP2 (CLP/saline)

Organism:
Mus musculus
Source name:
Cecal-Ligation-and-Puncture (CLP) Model of Sepsis + saline administration
Platform:
GPL6887
Series:
GSE24357
Download data
Sample
Accession:
GSM600354
ID:
300600354
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Supplemental Content

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