GEO DataSets

(Submitter supplied) Most epithelial ovarian cancers are thought to arise from different cells in the ovarian or fallopian tube epithelium. We hypothesized that these distinct cells-of-origin may play a role in determining ovarian tumor phenotype and also could inform the molecular classification of ovarian cancer. To test this hypothesis, we developed new methods to isolate and culture paired normal human ovarian (OV) and fallopian tube (FT) epithelial cells from multiple donors without cancer and identified a cell-of-origin gene expression signature that distinguished these cell types within the same patient. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS5321

Platform:

GPL570

12 Samples

Download data: CEL

Analysis of paired normal hTERT-immortalized ovarian (OCE) and fallopian tube (FNE) epithelial cell lines derived from two cancer-free donors. Results provide insight into gene signatures distinguishing the two cell types that could potentially identify the cell-of-origin of ovarian tumors.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 cell line, 2 individual, 4 other sets

Platform:

GPL570

Series:

GSE37648

12 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...

Organism:

Homo sapiens

602 DataSets

5645 Series

61 Related Platforms

171173 Samples

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