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Items: 4

1.

Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Mus musculus
Type:
Other; Expression profiling by high throughput sequencing
9 related Platforms
118 Samples
Download data: RCC, TXT
Series
Accession:
GSE52947
ID:
200052947
2.

Immune gene profile in lumbar spinal cord homogenate of healthy controls and ALS

(Submitter supplied) Amyotrophic lateral sclerosis (ALS) is a paralytic degenerative disease of the nervous system. In the SOD1 mouse model of ALS we found loss of the molecular and functional microglia signature associated with pronounced expression of miR-155 in SOD1 mice. We also found increased expression of miR-155 in the spinal cord of ALS subjects. Genetic ablation of miR-155 increased survival in SOD1 mice and reversed the abnormal microglial and monocyte molecular signature. more...
Organism:
Homo sapiens
Type:
Other
Platform:
GPL17980
20 Samples
Download data: RCC
Series
Accession:
GSE52672
ID:
200052672
3.

Nanostring Human Immunology Kit

(Submitter supplied) according to the manufacturer’s protocol
Organism:
Homo sapiens
2 Series
20 Samples
Download data
Platform
Accession:
GPL17980
ID:
100017980
4.

HC-A12-243

Organism:
Homo sapiens
Source name:
Whole spinal cord homogenate - post mortem
Platform:
GPL17980
Series:
GSE52672 GSE52947
Download data: RCC
Sample
Accession:
GSM1273894
ID:
301273894
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