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Status |
Public on Nov 24, 2014 |
Title |
Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice |
Organisms |
Homo sapiens; Mus musculus |
Experiment type |
Other Expression profiling by high throughput sequencing
|
Summary |
This SuperSeries is composed of the SubSeries listed below.
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Overall design |
Refer to individual Series
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Citation(s) |
25381879 |
Submission date |
Dec 03, 2013 |
Last update date |
May 15, 2019 |
Contact name |
Oleg Butovsky |
E-mail(s) |
obutovsky@rics.bwh.harvard.edu
|
Phone |
1-617-525-5313
|
Organization name |
Brigham and Women's Hospital, Harvard Medical School
|
Department |
Center of Neurologic Diseases
|
Lab |
Dr. Oleg Butovsky
|
Street address |
77 Avenue Louis Pasteur, Office 614
|
City |
Boston |
State/province |
MA |
ZIP/Postal code |
02115 |
Country |
USA |
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Platforms (9)
|
GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
GPL17873 |
NanoString nCounter Mouse miRNA expression chip (mirBase 15) |
GPL17978 |
Nanostring Human miRNA Assay Kit (mirBase 17) |
GPL17979 |
Nanostring mouse MG400 chip |
GPL17980 |
Nanostring Human Immunology Kit |
GPL17981 |
Nanostring mouse Inflammation kit |
GPL18002 |
MG400 custom Nanostring codesets |
GPL18014 |
Nanostring Mouse miRNA Assay Kit (mirBase 15) |
GPL18023 |
MG447 custom Nanostring codesets |
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Samples (118)
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This SuperSeries is composed of the following SubSeries:
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GSE52668 |
miRNA profile in SOD-155 microglia |
GSE52670 |
miRNA profile in lumbar spinal cord homogenate from healthy controls and ALS |
GSE52671 |
MG400 profile of spinal cord microglia during disease progression in SOD mice |
GSE52672 |
Immune gene profile in lumbar spinal cord homogenate of healthy controls and ALS |
GSE52673 |
Inflammation gene profile of sc-microglia in SOD mice |
GSE52803 |
MG400 profile of microglia from SOD miR155-KO mice |
GSE52898 |
miRNA profile in lumbar spinal cord homogenate of SOD-miR155 Tg mice |
GSE52946 |
miR-155 plays a crucial role in ALS and is an immune therapeutic target [RNA-Seq] |
GSE52959 |
MG447 profile of lumbar spinal cord homogenate from healthy controls and ALS |
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Relations |
BioProject |
PRJNA230510 |