GSM262241[Accession] - GEO DataSets

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Items: 3

Select item 2000104501.

Met induces mammary tumors with diverse histologies and is associated with poor outcome and human basal breast cancer

(Submitter supplied) Elevated Met receptor tyrosine kinase (RTK) expression correlates with poor outcome in breast cancer, yet a causal role for Met in the development of breast cancer has not been directly established. To examine this question, we generated a transgenic mouse model that targets expression of an oncogenic Met receptor (MetMut) to the mammary epithelium. We show that MetMut induces mammary tumors with a variety of histopathologies that exhibit gene expression profiles sharing similarities with human basal and luminal breast tumor subtypes. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platforms:: GPL4134 GPL2872
52 Samples

Download data: TXT

Series

Accession:: GSE10450

ID:: 200010450

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000028722.

Agilent-012694 Whole Mouse Genome G4122A (Feature Number version)

(Submitter supplied) Designed to truly represent all known genes in the mouse genome and their resulting transcripts, Agilent's Whole Mouse Genome Oligo microarray is comprised of 41,534 60-mer oligonucleotide probes representing over 41,000 mouse genes and transcripts. Content for this microarray was generated from leading public databases, including RefSeq, RIKEN, NIA, Ensembl, RIKEN, UCSC Goldenpath, and Unigene. Arrays of this design have barcodes that begin with 16012694 or 2512694. more...