GSM329057[Accession] - GEO DataSets

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Items: 4

Select item 2000131391.

LOX-1-dependent transcriptional regulation after oxidized LDL (OxLDL) treatment of human aortic endothelial cells.

(Submitter supplied) LOX-1 is the primary endothelial receptor for oxidized LDL in endothelial cells and plays a role in the development of atherosclerosis. Expression profiling was carried out on samples from HAECT cells over-expressing either LOX-1 or GFP control and treated with or without OxLDL over a time course of 2, 6, 12 and 24 Hours. The goal of the study was to identify genes expression changes activated by OxLDL binding to LOX-1 at several different time points.

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4262
Platform:: GPL570
54 Samples

Download data: CEL

Series

Accession:: GSE13139

ID:: 200013139

Select item 42622.

Oxidized low-density lipoprotein effect on LOX-1 overexpressing aortic endothelial cell line HAECT: time course

Analysis of oxidized-low-density lipoprotein receptor-1 (LOX-1)-overexpressing HAECT cells treated with OxLDL for up to 24 hrs. OxLDL is implicated as a proatherogenic factor. Results provide insight into molecular mechanisms underlying OxLDL-induced endothelial dysfunction and atherosclerosis.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 agent, 2 genotype/variation, 5 time sets

Platform:: GPL570
Series:: GSE13139
54 Samples

Download data: CEL

DataSet

Accession:: GDS4262

ID:: 4262

Select item 1000005703.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...