GSM3431772[Accession] - GEO DataSets

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Items: 4

Select item 2001213391.

A novel animal model for secondary progressive multiple sclerosis by oligodendroglia-specific conditional connexin 47 knockout

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by array

Platforms:: GPL21163 GPL20258
16 Samples

Download data: CEL, TXT

Series

Accession:: GSE121339

ID:: 200121339

Analyze with GEO2R

Select item 2001213372.

A novel animal model for secondary progressive multiple sclerosis by oligodendroglia-specific conditional connexin 47 knockout [Affy]

(Submitter supplied) Objective: To elucidate the role of Cx47 loss in chronic neuroinflammation and establish an SPMS model. Methods: Plp-CreERT; Cx47fl/fl mice were generated and administered tamoxifen to induce oligodendroglia-specific conditional knockout of Cx47 (Cx47 icKO). Ten days after tamoxifen treatment, Cx47 icKO mice and their control littermates were immunized by myelin oligodendrocyte glycoprotein peptide 35-55 to induce experimental autoimmune encephalomyelitis (EAE).

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL20258
8 Samples

Download data: CEL

Series

Accession:: GSE121337

ID:: 200121337

Analyze with GEO2R

Select item 1000202583.

[MTA-1_0] Affymetrix Mouse Transcriptome Array 1.0 [transcript (gene) CDF version]

(Submitter supplied) This platfrom configures to MTA-1_0.r1.gene.cdf. Annotation was derived from the Affymetrix annotation file MTA-1_0.na35.mm10.transcript.csv: #%create_date=Wed Apr 1 16:56:09 2015 PDT #%chip_type=MTA-1_0 #%lib_set_name=MTA-1_0 #%lib_set_version=r1 #%genome-species=Mus musculus #%genome-version=mm10 #%genome-version-ucsc=mm10 #%genome-version-ncbi=38 #%genome-version-create_date=2011-12-00 #%genome-lifted-method=psl-map.pl #%genome-lifted_from-species=Mus musculus #%genome-lifted_from-version-ucsc=mm10 #%genome-lifted_from-version-ncbi=38 #%netaffx-annotation-date=2014-10-31 #%netaffx-annotation-netaffx-build=35 Protocol: See manufacturers website