GEO DataSets

(Submitter supplied) We profiled Myc binding in a normal breast cell-line (MCF10A) under basal conditions after ectopic expression of Myc. We showed that ectopic Myc expression increases tumour formation in vivo and in vitro. We then profiled genome-wide Myc binding using Agilent promoter arrays in MCF10A cells expressing wild-type and ectopic Myc. We show that Myc binds to a greater number of spots in wild-type than in Myc cells, but that some targets are unique to each condition. more...

Organism:

Homo sapiens

Type:

Expression profiling by array; Genome binding/occupancy profiling by array

Platforms:

GPL4124 GPL4125 GPL8019

56 Samples

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(Submitter supplied) We profiled Myc binding in a normal breast cell-line (MCF10A) under basal conditions after ectopic expression of Myc. We showed that ectopic Myc expression increases tumour formation in vivo and in vitro. We then profiled genome-wide Myc binding using Agilent promoter arrays in MCF10A cells expressing wild-type and ectopic Myc. We show that Myc binds to a greater number of spots in wild-type than in Myc cells, but that some targets are unique to each condition. more...

Organism:

Homo sapiens

Type:

Genome binding/occupancy profiling by array

Platforms:

GPL4125 GPL4124

40 Samples

Download data: TIFF, TXT

(Submitter supplied) Human Promoter ChIP-on-Chip Set 244K 1 of 2 Arrays of this design have barcodes that begin with 16014706 or 2514706. Orientation: Features are numbered numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. The ID column represents the Agilent Feature Extraction feature number. more...

Organism:

Homo sapiens

25 Series

1 Related Platform

130 Samples

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