Similar studies for GEO DataSets (Select 200037815) - GEO DataSets

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Items: 11

Select item 2000378151.

DNA methylation and expression profiling study for bladder cancer [gene expression]

(Submitter supplied) The DNA methylation patterns associated with the development and progression of cancer. The aim of the present study was to identify novel methylation markers that can discriminate between normal and Non-muscle-invasive bladder cancer (NMIBC), and between good and poor prognosis using microarray analysis of DNA methylation and RNA expression patterns in NMIBC patients. From the 24 matched microarray-based DNA methylation and gene expression profiling data set, tumor specific hypermethylated genes were selected and clinical relevance of these genes were verified by quantitative PQS analyses. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6102
24 Samples

Download data: TXT

Series

Accession:: GSE37815

ID:: 200037815

Select item 2000378172.

DNA methylation and expression profiling study for bladder cancer

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array; Methylation profiling by array

Platforms:: GPL8490 GPL6102
48 Samples

Download data

Series

Accession:: GSE37817

ID:: 200037817

Select item 2000378163.

DNA methylation and expression profiling study for bladder cancer [methylation]

Organism:: Homo sapiens

Type:: Methylation profiling by array

Platform:: GPL8490
24 Samples

Download data: TXT

Series

Accession:: GSE37816

ID:: 200037816

Select item 2000358244.

Genome-wide DNA methylation study in bladder cancer

(Submitter supplied) Genome-wide DNA methylation profiles were determined on a set of fresh 44 bladder cancer tissues using normal blood as control. DNA amplicons were prepared using Differential Methylation Hybridization (DMH) method, subsequently hybridized on to the Agilent Human CpG island Microarray. The goal was to unravel the DNA methylation patterns in different subgropus of bladder cancer along with finding markers for progresssion and early diagnosis.

Organism:: Homo sapiens

Type:: Methylation profiling by genome tiling array

Platform:: GPL4126
44 Samples

Download data: TXT

Series

Accession:: GSE35824

ID:: 200035824

Select item 2000273745.

Methylation profile in breast cancer

(Submitter supplied) Agilent CpG microarray in combination with enriched methylated DNA by a MBD protein were carried out in each pool of genomic DNA from primary breast tumor and matched adjacent normal tissues.

Organism:: Homo sapiens

Type:: Methylation profiling by genome tiling array

Platform:: GPL9767
2 Samples

Download data: TXT

Series

Accession:: GSE27374

ID:: 200027374

Select item 2000338396.

Identification of a novel set of DNA methylation markers in bladder cancer using MBD-methylCap/seq and urine DNA screening in a Chinese population

(Submitter supplied) The aim of the present study was to identify novel DNA methylation markers in bladder cancer (BCa) through genome-wide profiling of bladder cancer cell lines and subsequent MSP screening in urine samples. Experimental Design: MBD methylCap/seq was carried out to screen differentially methylated CpG islands using two BCa cell lines (5637 and T24) and two normal bladder mucosa (BM) samples. The top one hundred most hypermethylated targets were screened using Methylation Specific PCR (MSP) in small and big cohort of urine samples from BCa patients and normal controls. more...

Organism:: Homo sapiens

Type:: Methylation profiling by high throughput sequencing

Platform:: GPL9052
2 Samples

Download data: WIG

Series

Accession:: GSE33839

ID:: 200033839

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000352637.

Methylation in breast cancer vs. normal tissue

(Submitter supplied) We applied a combination of Methyl-CpG Immunoprecipitation (MCIp) and Human CpG Island microarrays to identify aberrant DNA methylation in eight low-grade breast invasive carcinomas and two pre-invasive breast tumors against ten normal breast tissues.

Organism:: Homo sapiens

Type:: Methylation profiling by genome tiling array

Platform:: GPL9767
10 Samples

Download data: TXT

Series

Accession:: GSE35263

ID:: 200035263

Select item 2000135078.

Predective Value of Prognosis-Related Gene Expression Study in Primary Bladder Cancer

(Submitter supplied) This study aimed to identify the genetic signatures associated with disease prognosis in bladder cancer. We used 165 primary bladder cancer samples, 23 recurrent non-muscle invasive tumor tissues, 58 normal looking bladder mucosae surrounding cancer and 10 normal bladder mucosae for microarray analysis. Hierarchical clustering was used to stratify the prognosis-related gene classifiers. For validation, real-time reverse-transcriptase polymerase chain reaction (RT-PCR) of top-ranked 14 genes was performed. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6102
256 Samples

Download data: TXT, XLS

Series

Accession:: GSE13507

ID:: 200013507

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000194239.

Predictive Gene Signatures as Strong Prognostic Indicators of the Effectiveness of BCG Immunotherapy

(Submitter supplied) Full title: Predictive Gene Signatures as Strong Prognostic Indicators of the Effectiveness of Bacillus Calmette–Guérin (BCG) Immunotherapy in Primary pT1 Bladder Cancers Intravesical BCG immunotherapy is effective in prevention of recurrence and progression in many cases of non-muscle invasive bladder cancer, but many patients fail to respond. This study identified predictive gene signatures in primary pT1 bladder cancer with BCG immunotherapy. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6102
48 Samples

Download data: TXT, XLS

Series

Accession:: GSE19423

ID:: 200019423

Select item 20023344710.

Single-cell transcriptome analysis of small cell neuroendocrine tumor of the endometrium reveals ISL1 as a potential biomarker for diagnosis and treatment

(Submitter supplied) In this study, we performed single-cell RNA sequencing on a specimen from a patient with endometrial neuroendocrine carcinoma pathologically diagnosed. By analyzing the data, we found that the expression of Islet-1 was significantly up-regulated in tumor cells. Furthermore, we verified it in neuroendocrine tumor cell lines, and obtained cells with high expression of Islet-1 and cells with low expression of Islet-1 by flow sorting. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL18573
4 Samples

Download data: MTX

Series

Accession:: GSE233447

ID:: 200233447

PubMed Similar studies

Select item 20018392011.

Immune profiles and DNA methylation alterations related to non-muscle-invasive bladder cancer outcomes

(Submitter supplied) Non-muscle-invasive bladder cancer (NMIBC) patients receive frequent monitoring because ≥ 70% will have recurrent disease. However, screening is invasive, expensive, and associated with significant morbidity making bladder cancer the most expensive cancer to treat per capita. There is an urgent need to expand the understanding of markers related to recurrence and survival outcomes of NMIBC. Our results expand on the knowledge of immune profiles and methylation alteration associated with NMIBC outcomes and represent a first step toward the development of DNA methylation-based biomarkers of tumor recurrence.