GEO DataSets

(Submitter supplied) Comparison of RNA expression profiles from NTHi strain R2866 expressing methyltransferase ModA10 (ON) or not (LOCK_OFF).

Organism:

Haemophilus influenzae R2866

Type:

Expression profiling by high throughput sequencing

Platform:

GPL26504

6 Samples

Download data: TXT

(Submitter supplied) Comparison of RNA expression profiles from NTHi strain 723 strains expressing methyltransferase ModA2 (ON) or not (OFF)

Organism:

Haemophilus influenzae

Type:

Expression profiling by high throughput sequencing

Platform:

GPL19560

6 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Haemophilus influenzae

Type:

Expression profiling by high throughput sequencing

Platform:

GPL25730

18 Samples

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(Submitter supplied) comparison of RNA expression profiles from NTHi strain 1209 strains expressing methyltransferase ModA9 (ON) or not (OFF)

Organism:

Haemophilus influenzae

Type:

Expression profiling by high throughput sequencing

Platform:

GPL25730

6 Samples

Download data: TXT

(Submitter supplied) comparison of RNA expression profiles from NTHi strain 477 strains expressing methyltransferase ModA5 (ON) or not (OFF)

Organism:

Haemophilus influenzae

Type:

Expression profiling by high throughput sequencing

Platform:

GPL25730

6 Samples

Download data: TXT

(Submitter supplied) comparison of RNA expression profiles from NTHi strain C486 strains expressing methyltransferase ModA4 (ON) or not (OFF)

Organism:

Haemophilus influenzae

Type:

Expression profiling by high throughput sequencing

Platform:

GPL25730

6 Samples

Download data: TXT

(Submitter supplied) Comparison of RNA expression profiles from NTHi strain 84P36H1 strains expressing methyltransferase ModA18 (ON) or not (OFF).

Organism:

Haemophilus influenzae

Type:

Expression profiling by high throughput sequencing

Platform:

GPL25730

6 Samples

Download data: TXT

(Submitter supplied) Comparison of RNA expression profiles from NTHi strain 10P129H1 strains expressing methyltransferase ModA15 (ON) or not (OFF).

Organism:

Haemophilus influenzae

Type:

Expression profiling by high throughput sequencing

Platform:

GPL25730

6 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Haemophilus influenzae R2866; Haemophilus influenzae

Type:

Expression profiling by array

Platform:

GPL18059

64 Samples

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(Submitter supplied) Gene expresison profiles of the R2866 WT and R2866Δ0112 mutant gorwn 7 hours in supplemented brain-heart infusion medium. This experiment was conducted to determine the effects of R2866_0112 gene deletion on overall gene expression profile. The results from this study are further discussed in: Modified lipooligosaccharide structure protects nontypeable Haemophilus influenzae from IgM-mediated complement killing in experimental otitis media. more...

Organism:

Haemophilus influenzae; Haemophilus influenzae R2866

Type:

Expression profiling by array

Platform:

GPL18059

32 Samples

Download data: PAIR

(Submitter supplied) Gene expresison profiles of the R2866 WT and R2866Δ0112 mutant gorwn 4 hours in supplemented brain-heart infusion medium. This experiment was conducted to determine the effects of R2866_0112 gene deletion on overall gene expression profile. The results from this study are further discussed in: Modified lipooligosaccharide structure protects nontypeable Haemophilus influenzae from IgM-mediated complement killing in experimental otitis media. more...

Organism:

Haemophilus influenzae; Haemophilus influenzae R2866

Type:

Expression profiling by array

Platform:

GPL18059

32 Samples

Download data: PAIR

(Submitter supplied) Many host-adapted bacterial pathogens contain DNA methyltransferases (mod genes) that are subject to phase-variable expression (high-frequency reversible ON/OFF switching of gene expression). In Haemophilus influenzae, Neissera Meningtidis and Neisseria Gonorrhoeae, the random switching of the modA gene, associated with a phase variable type III restriction modification (R-M) system, controls expression of a phase-variable regulon of genes (a “phasevarion”), via differential methylation of the genome in the modA ON and OFF states. more...

Organism:

Helicobacter pylori P12; Helicobacter pylori

Type:

Expression profiling by array

Platform:

GPL11628

6 Samples

Download data: TXT

(Submitter supplied) Characterization of host-pathogen interactions is critical for the development of next-generation therapies and vaccines. Classical approaches involve the use of transformed cell lines and/or animal models which may not reflect the complexity and response of the human host. We reconstituted the ciliated human bronchial epithelium in vitro using primary bronchial epithelial cells to simultaneously monitor the infection-linked global changes in nontypeable Haemophilus influenzae (NTHi) and infected host epithelia gene expression by dual RNA-seq. more...

Organism:

Homo sapiens; Haemophilus influenzae

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL16791 GPL19560

24 Samples

Download data: TXT