These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

1. NM_001386282.1 → NP_001373211.1  alpha-2-macroglobulin precursor

   Status: VALIDATED

   Source sequence(s)

   CR626907

   UniProtKB/TrEMBL

   A0A8M9QPQ0

   Conserved Domains (5) summary

   COG2373
   Location:128 → 1430

   YfaS; Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family [General function prediction only]

   cd02897
   Location:948 → 1234

   A2M_2; Proteins similar to alpha2-macroglobulin (alpha (2)-M). This group also contains the pregnancy zone protein (PZP). Alpha(2)-M and PZP are broadly specific proteinase inhibitors. Alpha (2)-M is a major carrier protein in serum. The structural thioester ...

   pfam00207
   Location:729 → 817

   A2M; Alpha-2-macroglobulin family

   pfam07677
   Location:1341 → 1431

   A2M_recep; A-macroglobulin receptor

   pfam07703
   Location:459 → 609

   A2M_N_2; Alpha-2-macroglobulin family N-terminal region