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grwd-1 Glutamate-rich WD repeat-containing protein 1 [ Caenorhabditis elegans ]

Gene ID: 175701, updated on 12-Jun-2024

Summary

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Gene symbol
grwd-1
Gene description
Glutamate-rich WD repeat-containing protein 1
Locus tag
CELE_Y54H5A.1
See related
AllianceGenome:WB:WBGene00021899
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be located in nucleus. Orthologous to human GRWD1 (glutamate rich WD repeat containing 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See grwd-1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
5
Sequence:
Chromosome: III; NC_003281.10 (5153543..5155436)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Protein HGH1 homolog Neighboring gene ncRNA Neighboring gene RNA-binding protein 42 Neighboring gene putative cytosolic Fe-S cluster assembly factor oxy-4 Neighboring gene pseudo Neighboring gene Trafficking protein particle complex subunit 2-like protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in ribosome biogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Glutamate-rich WD repeat-containing protein 1
NP_498091.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    5153543..5155436
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_065690.8 → NP_498091.1  Glutamate-rich WD repeat-containing protein 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_498091.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9N393
    Conserved Domains (3) summary
    sd00039
    Location:232 → 273
    7WD40; WD40 repeat [structural motif]
    pfam12265
    Location:54 → 122
    CAF1C_H4-bd; Histone-binding protein RBBP4 or subunit C of CAF1 complex
    cl29593
    Location:182 → 401
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein
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