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F55F10.1 Midasin;VWFA domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 186322, updated on 23-Nov-2023

Summary

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Gene symbol
F55F10.1
Gene description
Midasin;VWFA domain-containing protein
Primary source
WormBase:WBGene00018898
Locus tag
CELE_F55F10.1
See related
AllianceGenome:WB:WBGene00018898
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable ATP binding activity and ATP hydrolysis activity. Predicted to be involved in rRNA processing and ribosomal large subunit assembly. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of preribosome, large subunit precursor. Orthologous to human MDN1 (midasin AAA ATPase 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See F55F10.1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
20
Sequence:
Chromosome: IV; NC_003282.8 (4360837..4386531)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene serine--tRNA ligase Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene Transaldolase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Large ribosomal subunit protein eL8

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules. Marnik EA, et al. Genetics, 2019 Nov. PMID 31506335, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in ribosomal large subunit assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ribosomal large subunit assembly IEA
Inferred from Electronic Annotation
more info
  
involved_in ribosomal large subunit export from nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of preribosome, large subunit precursor IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Midasin;VWFA domain-containing protein
NP_001367899.1
  • Confirmed by transcript evidence
NP_001368166.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    4360837..4386531
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001380187.2 → NP_001367899.1  VWFA domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    O61851
    Conserved Domains (2) summary
    COG5271
    Location:610 → 2124
    MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
    cd01460
    Location:1872 → 2129
    vWA_midasin; VWA_Midasin: Midasin is a member of the AAA ATPase family. The proteins of this family are unified by their common archetectural organization that is based upon a conserved ATPase domain. The AAA domain of midasin contains six tandem AAA protomers. The ...

  2. NM_001380186.1 → NP_001368166.1  Midasin [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    L8E6W9
    Conserved Domains (1) summary
    COG5271
    Location:70 → 4355
    MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
Nucleotide Protein
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