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Sh3tc1 SH3 domain and tetratricopeptide repeats 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 305441, updated on 3-Apr-2024

Summary

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Official Symbol
Sh3tc1provided by RGD
Official Full Name
SH3 domain and tetratricopeptide repeats 1provided by RGD
Primary source
RGD:1305610
See related
Ensembl:ENSRNOG00000007993 AllianceGenome:RGD:1305610
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Orthologous to human SH3TC1 (SH3 domain and tetratricopeptide repeats 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 133.2), Lung (RPKM 86.7) and 7 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
14q21
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (79230322..79274622)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (75005691..75050001)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (80184814..80229207)

Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134481855 Neighboring gene actin binding LIM protein family, member 2 Neighboring gene HtrA serine peptidase 3 Neighboring gene acyl-CoA oxidase 3, pristanoyl Neighboring gene tRNA methyltransferase 44

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mutations in a gene encoding a novel SH3/TPR domain protein cause autosomal recessive Charcot-Marie-Tooth type 4C neuropathy. Senderek J, et al. Am J Hum Genet, 2003 Nov. PMID 14574644, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

General protein information

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Preferred Names
SH3 domain and tetratricopeptide repeat-containing protein 1
Names
SH3 domain and tetratricopeptide repeats-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107226.1 → NP_001100696.1  SH3 domain and tetratricopeptide repeat-containing protein 1

    See identical proteins and their annotated locations for NP_001100696.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473963
    UniProtKB/TrEMBL
    A6IJZ0, D3ZLQ9
    Related
    ENSRNOP00000010784.6, ENSRNOT00000010784.7
    Conserved Domains (3) summary
    sd00006
    Location:1162 → 1189
    TPR; TPR repeat [structural motif]
    pfam13424
    Location:1161 → 1233
    TPR_12; Tetratricopeptide repeat
    cl17036
    Location:312 → 366
    SH3; Src Homology 3 domain superfamily

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086032.1 Reference GRCr8

    Range
    79230322..79274622
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006251127.5 → XP_006251189.1  SH3 domain and tetratricopeptide repeat-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006251189.1

    UniProtKB/TrEMBL
    A6IJZ0, D3ZLQ9
    Conserved Domains (3) summary
    sd00006
    Location:1162 → 1189
    TPR; TPR repeat [structural motif]
    pfam13424
    Location:1161 → 1233
    TPR_12; Tetratricopeptide repeat
    cl17036
    Location:312 → 366
    SH3; Src Homology 3 domain superfamily

  2. XM_006251126.5 → XP_006251188.1  SH3 domain and tetratricopeptide repeat-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006251188.1

    UniProtKB/TrEMBL
    A6IJZ0, D3ZLQ9
    Conserved Domains (3) summary
    sd00006
    Location:1162 → 1189
    TPR; TPR repeat [structural motif]
    pfam13424
    Location:1161 → 1233
    TPR_12; Tetratricopeptide repeat
    cl17036
    Location:312 → 366
    SH3; Src Homology 3 domain superfamily

  3. XM_063273148.1 → XP_063129218.1  SH3 domain and tetratricopeptide repeat-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A6IJZ0

  4. XM_063273150.1 → XP_063129220.1  SH3 domain and tetratricopeptide repeat-containing protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8I5ZL28

  5. XM_063273149.1 → XP_063129219.1  SH3 domain and tetratricopeptide repeat-containing protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8I5ZL28

  6. XM_006251128.5 → XP_006251190.1  SH3 domain and tetratricopeptide repeat-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006251190.1

    UniProtKB/TrEMBL
    A6IJZ0, D3ZLQ9
    Conserved Domains (3) summary
    sd00006
    Location:1162 → 1189
    TPR; TPR repeat [structural motif]
    pfam13424
    Location:1161 → 1233
    TPR_12; Tetratricopeptide repeat
    cl17036
    Location:312 → 366
    SH3; Src Homology 3 domain superfamily

  7. XM_039091961.2 → XP_038947889.1  SH3 domain and tetratricopeptide repeat-containing protein 1 isoform X4

    Conserved Domains (3) summary
    sd00006
    Location:605 → 655
    TPR; TPR repeat [structural motif]
    pfam13424
    Location:672 → 733
    TPR_12; Tetratricopeptide repeat
    cl17036
    Location:312 → 366
    SH3; Src Homology 3 domain superfamily

  8. XM_006251130.5 → XP_006251192.1  SH3 domain and tetratricopeptide repeat-containing protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8I5ZL28, D3ZLQ9
    Related
    ENSRNOP00000078567.1
    Conserved Domains (3) summary
    sd00006
    Location:1137 → 1164
    TPR; TPR repeat [structural motif]
    pfam13424
    Location:1136 → 1208
    TPR_12; Tetratricopeptide repeat
    cl17036
    Location:287 → 341
    SH3; Src Homology 3 domain superfamily

  9. XM_006251125.5 → XP_006251187.1  SH3 domain and tetratricopeptide repeat-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006251187.1

    UniProtKB/TrEMBL
    A6IJZ0, D3ZLQ9
    Conserved Domains (3) summary
    sd00006
    Location:1162 → 1189
    TPR; TPR repeat [structural motif]
    pfam13424
    Location:1161 → 1233
    TPR_12; Tetratricopeptide repeat
    cl17036
    Location:312 → 366
    SH3; Src Homology 3 domain superfamily

  10. XM_039091959.2 → XP_038947887.1  SH3 domain and tetratricopeptide repeat-containing protein 1 isoform X3

    UniProtKB/TrEMBL
    D3ZLQ9
    Conserved Domains (3) summary
    sd00006
    Location:1095 → 1122
    TPR; TPR repeat [structural motif]
    pfam13424
    Location:1098 → 1166
    TPR_12; Tetratricopeptide repeat
    cl17036
    Location:245 → 299
    SH3; Src Homology 3 domain superfamily

  11. XM_039091962.2 → XP_038947890.1  SH3 domain and tetratricopeptide repeat-containing protein 1 isoform X5

    Conserved Domains (2) summary
    sd00006
    Location:813 → 840
    TPR; TPR repeat [structural motif]
    pfam13424
    Location:816 → 884
    TPR_12; Tetratricopeptide repeat
Nucleotide Protein Strain
Heading Accession and Version

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