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Lrrc74a leucine rich repeat containing 74A [ Rattus norvegicus (Norway rat) ]

Gene ID: 314328, updated on 13-Apr-2024

Summary

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Symbol
Lrrc74aprovided by RGD
Full Name
leucine rich repeat containing 74Aprovided by RGD
Primary source
RGD:1564488
See related
Ensembl:ENSRNOG00000052456 AllianceGenome:RGD:1564488
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Lrrc74
Summary
Orthologous to human LRRC74A (leucine rich repeat containing 74A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward (RPKM 227.6) See more
Orthologs
human mouse all
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Genomic context

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See Lrrc74a in Genome Data Viewer
Location:
6q31
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (112117226..112147152)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (106386276..106417112)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (110681551..110776904)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene vasohibin 1 Neighboring gene angel homolog 1 Neighboring gene uncharacterized LOC108351370 Neighboring gene uncharacterized LOC134479453

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC114373, MGC156476

General protein information

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Preferred Names
leucine-rich repeat-containing protein 74A
Names
leucine rich repeat containing 74
leucine-rich repeat-containing protein 74
uncharacterized protein C14orf166B homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001037783.2 → NP_001032872.2  leucine-rich repeat-containing protein 74A

    See identical proteins and their annotated locations for NP_001032872.2

    Status: VALIDATED

    Source sequence(s)
    BC127444, CR475527, JAXUCZ010000006
    UniProtKB/Swiss-Prot
    A0JPI9, Q4KLZ5
    Related
    ENSRNOP00000086029.1, ENSRNOT00000098897.1
    Conserved Domains (2) summary
    sd00033
    Location:148 → 176
    LRR_RI; leucine-rich repeat [structural motif]
    cl39015
    Location:91 → 353
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    112117226..112147152
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039112315.2 → XP_038968243.1  leucine-rich repeat-containing protein 74A isoform X3

    UniProtKB/TrEMBL
    A0A0G2JWD4
    Conserved Domains (2) summary
    sd00034
    Location:148 → 176
    LRR_AMN1; leucine-rich repeat [structural motif]
    cl39015
    Location:91 → 331
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

  2. XM_039112314.2 → XP_038968242.1  leucine-rich repeat-containing protein 74A isoform X2

    Conserved Domains (2) summary
    sd00033
    Location:113 → 140
    LRR_RI; leucine-rich repeat [structural motif]
    cl39015
    Location:81 → 317
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

  3. XM_039112313.2 → XP_038968241.1  leucine-rich repeat-containing protein 74A isoform X1

    UniProtKB/TrEMBL
    A0A8I6A2M8
    Related
    ENSRNOP00000085143.1
    Conserved Domains (2) summary
    sd00033
    Location:148 → 176
    LRR_RI; leucine-rich repeat [structural motif]
    cl39015
    Location:91 → 353
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

  4. XM_039112316.2 → XP_038968244.1  leucine-rich repeat-containing protein 74A isoform X4

    Conserved Domains (2) summary
    sd00033
    Location:148 → 176
    LRR_RI; leucine-rich repeat [structural motif]
    cl39015
    Location:91 → 320
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

  5. XM_039112318.2 → XP_038968246.1  leucine-rich repeat-containing protein 74A isoform X6

    Conserved Domains (2) summary
    sd00033
    Location:148 → 176
    LRR_RI; leucine-rich repeat [structural motif]
    cl39015
    Location:91 → 320
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

  6. XM_039112319.2 → XP_038968247.1  leucine-rich repeat-containing protein 74A isoform X7

    Conserved Domains (2) summary
    sd00031
    Location:142 → 176
    LRR_1; leucine-rich repeat [structural motif]
    cl39015
    Location:86 → 227
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

  7. XM_063261945.1 → XP_063118015.1  leucine-rich repeat-containing protein 74A isoform X7

  8. XM_063261946.1 → XP_063118016.1  leucine-rich repeat-containing protein 74A isoform X8

  9. XM_063261947.1 → XP_063118017.1  leucine-rich repeat-containing protein 74A isoform X9

  10. XM_039112325.2 → XP_038968253.1  leucine-rich repeat-containing protein 74A isoform X9

    Conserved Domains (1) summary
    cl39015
    Location:86 → 184
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

  11. XM_039112317.2 → XP_038968245.1  leucine-rich repeat-containing protein 74A isoform X5

    Conserved Domains (2) summary
    sd00033
    Location:11 → 38
    LRR_RI; leucine-rich repeat [structural motif]
    cl39015
    Location:13 → 244
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0JPI9.1 GenPept UniProtKB/Swiss-Prot:A0JPI9

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Chemical Information
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