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Jon25Bii Jonah 25Bii [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33707, updated on 10-May-2024

Summary

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Official Symbol
Jon25Biiprovided by FlyBase
Official Full Name
Jonah 25Biiprovided by FlyBase
Primary source
FLYBASE:FBgn0031654
Locus tag
Dmel_CG8869
See related
AllianceGenome:FB:FBgn0031654
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
25B; CG8869; Dmel\CG8869; Jon25; Jon25B; Jon25ii; SP112
Summary
Enables serine hydrolase activity. Predicted to be involved in proteolysis. Is expressed in organism. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See Jon25Bii in Genome Data Viewer
Location:
25B4-25B4; 2-14 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (4952243..4953136, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (4952243..4953136, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene beta subunit of type I geranylgeranyl transferase Neighboring gene jetlag Neighboring gene Jonah 25Biii Neighboring gene Jonah 25Bi Neighboring gene Marcal1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The detection of Jonah gene transcripts in Drosophila by in situ hybridization. Akam ME, et al. EMBO J, 1985 Jan. PMID 2410252, Free PMC Article
  2. Developmental and functional analysis of Jonah gene expression. Carlson JR, et al. Dev Biol, 1985 Apr. PMID 2416611
  3. Drosophila melanogaster positive transcriptional elongation factors regulate metabolic and sex-biased expression in adults. Yang H, et al. BMC Genomics, 2017 May 18. PMID 28521739, Free PMC Article
  4. Juvenile hormone regulation of Drosophila aging. Yamamoto R, et al. BMC Biol, 2013 Jul 17. PMID 23866071, Free PMC Article
  5. Aminergic Signaling Controls Ovarian Dormancy in Drosophila. Andreatta G, et al. Sci Rep, 2018 Feb 1. PMID 29391447, Free PMC Article

See all (58) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables serine hydrolase activity HDA PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables serine-type endopeptidase activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
involved_in proteolysis ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
jonah 25Bii
Names
CG8869-PA
CG8869-PB
Jon25Bii-PA
Jon25Bii-PB
jonah 25B
NP_001285608.1
NP_608882.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    4952243..4953136 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001298679.1 → NP_001285608.1  jonah 25Bii, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285608.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q86P28, Q9VMX8
    Conserved Domains (2) summary
    smart00020
    Location:42 → 268
    Tryp_SPc; Trypsin-like serine protease
    cd00190
    Location:43 → 271
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

  2. NM_135038.2 → NP_608882.1  jonah 25Bii, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608882.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q86P28, Q9VMX8
    Related
    FBpp0078691
    Conserved Domains (2) summary
    smart00020
    Location:42 → 268
    Tryp_SPc; Trypsin-like serine protease
    cd00190
    Location:43 → 271
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q86P28 Q86P28
Q9VMX8 Q9VMX8

Gene LinkOut

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