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klhdc3 kelch domain containing 3 [ Danio rerio (zebrafish) ]

Gene ID: 406553, updated on 27-Mar-2024

Summary

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Official Symbol
klhdc3provided by ZNC
Official Full Name
kelch domain containing 3provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2426
See related
AllianceGenome:ZFIN:ZDB-GENE-040426-2426
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:85727
Summary
Predicted to enable chromatin binding activity. Predicted to be active in cytoplasm. Orthologous to human KLHDC3 (kelch domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See klhdc3 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
11
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (51978642..52002864)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (51769322..51778685)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene type I inositol 1,4,5-trisphosphate 5-phosphatase Neighboring gene kinesin light chain 1b Neighboring gene solute carrier family 30 member 10 Neighboring gene lysocardiolipin acyltransferase 1 Neighboring gene transmembrane protein 121-like Neighboring gene neuronal PAS domain protein 4 like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Morphologic and functional characterization of granulocytes and macrophages in embryonic and adult zebrafish. Lieschke GJ, et al. Blood, 2001 Nov 15. PMID 11698295
  2. Endothelial versus pronephron fate decision is modulated by the transcription factors Cloche/Npas4l, Tal1, and Lmo2. Mattonet K, et al. Sci Adv, 2022 Sep 2. PMID 36044573, Free PMC Article
  3. Why does the zebrafish cloche mutant develop lens cataract? Posner M, et al. PLoS One, 2019. PMID 30861003, Free PMC Article
  4. Cloche is a bHLH-PAS transcription factor that drives haemato-vascular specification. Reischauer S, et al. Nature, 2016 Jul 14. PMID 27411634
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  

General protein information

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Preferred Names
kelch domain-containing protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    51978642..52002864
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021480925.1 → XP_021336600.1  kelch domain-containing protein 3

    UniProtKB/TrEMBL
    A0A8M9QNZ4
    Conserved Domains (2) summary
    sd00038
    Location:128 → 173
    Kelch; KELCH repeat [structural motif]
    cl26061
    Location:9 → 198
    PLN02193; nitrile-specifier protein

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_213269.1: Suppressed sequence

    Description
    NM_213269.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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