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anp32e acidic (leucine-rich) nuclear phosphoprotein 32 family, member E [ Danio rerio (zebrafish) ]

Gene ID: 406562, updated on 27-Mar-2024

Summary

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Official Symbol
anp32eprovided by ZNC
Official Full Name
acidic (leucine-rich) nuclear phosphoprotein 32 family, member Eprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2448
See related
Ensembl:ENSDARG00000054804 AllianceGenome:ZFIN:ZDB-GENE-040426-2448
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:65995; zgc:85827; wu:fb22e03; wu:fc04c12; wu:fc19a08; wu:fc79f04; wu:fi39c10
Summary
Predicted to enable histone binding activity and phosphatase inhibitor activity. Predicted to be involved in histone exchange and regulation of apoptotic process. Predicted to act upstream of or within chromatin organization. Predicted to be located in cytoplasm. Predicted to be part of Swr1 complex. Predicted to be active in nucleus. Orthologous to human ANP32E (acidic nuclear phosphoprotein 32 family member E). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See anp32e in Genome Data Viewer
Location:
chromosome: 19
Exon count:
7
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (42328442..42341815)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (42759005..42772378)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene si:ch211-191i18.2 Neighboring gene cocaine- and amphetamine-regulated transcript 4 Neighboring gene pleckstrin homology domain containing, family O member 1a Neighboring gene vacuolar protein sorting 45 homolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Quantitative proteomics analysis of zebrafish exposed to sub-lethal dosages of β-methyl-amino-L-alanine (BMAA). Frøyset AK, et al. Sci Rep, 2016 Jul 12. PMID 27404450, Free PMC Article
  2. Placeholder Nucleosomes Underlie Germline-to-Embryo DNA Methylation Reprogramming. Murphy PJ, et al. Cell, 2018 Feb 22. PMID 29456083
  3. Identification of nodal signaling targets by array analysis of induced complex probes. Dickmeis T, et al. Dev Dyn, 2001 Dec. PMID 11748827
  4. The Anp32 family of proteins containing leucine-rich repeats. Matilla A, et al. Cerebellum, 2005. PMID 15895553
  5. Olfactory imprinting is correlated with changes in gene expression in the olfactory epithelia of the zebrafish. Harden MV, et al. J Neurobiol, 2006 Nov. PMID 17013923

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Anp32e protects against accumulation of H2A.Z at Sox motif containing promoters during zebrafish gastrulation.
    Title: Anp32e protects against accumulation of H2A.Z at Sox motif containing promoters during zebrafish gastrulation.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Clone Names

  • MGC113940

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables histone binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables histone binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables histone chaperone activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables phosphatase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within chromatin organization IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of apoptotic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of Swr1 complex ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
acidic leucine-rich nuclear phosphoprotein 32 family member E

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213277.1 → NP_998442.1  acidic leucine-rich nuclear phosphoprotein 32 family member E

    See identical proteins and their annotated locations for NP_998442.1

    Status: PROVISIONAL

    Source sequence(s)
    BC068403
    UniProtKB/Swiss-Prot
    Q6NUW5
    Related
    ENSDARP00000071527.3, ENSDART00000077059.5
    Conserved Domains (3) summary
    sd00031
    Location:44 → 65
    LRR_1; leucine-rich repeat [structural motif]
    pfam12799
    Location:89 → 130
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:64 → 125
    LRR_8; Leucine rich repeat

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    42328442..42341815
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6NUW5.1 GenPept UniProtKB/Swiss-Prot:Q6NUW5

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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