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epb41l3a erythrocyte membrane protein band 4.1-like 3a [ Danio rerio (zebrafish) ]

Gene ID: 445478, updated on 27-Mar-2024

Summary

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Official Symbol
epb41l3aprovided by ZNC
Official Full Name
erythrocyte membrane protein band 4.1-like 3aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040822-8
See related
Ensembl:ENSDARG00000002255 AllianceGenome:ZFIN:ZDB-GENE-040822-8
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:92004
Summary
Predicted to enable actin binding activity and structural molecule activity. Acts upstream of or within regulation of excitatory synapse assembly. Predicted to be located in cell-cell junction; cytoskeleton; and plasma membrane. Is expressed in nervous system; optic cup; and trigeminal placode. Orthologous to human EPB41L3 (erythrocyte membrane protein band 4.1 like 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See epb41l3a in Genome Data Viewer
Location:
chromosome: 24
Exon count:
29
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (41927330..41986897)
105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (42055974..42089258, complement)

Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene Rho GTPase activating protein 28 Neighboring gene L3MBTL histone methyl-lysine binding protein 4 Neighboring gene transmembrane protein 200C, genome duplicate a Neighboring gene zinc finger and BTB domain containing 14 Neighboring gene DNA topoisomerase I mitochondrial

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. 4.1Ba is necessary for glutamatergic synapse formation in the sensorimotor circuit of developing zebrafish. Fierro J Jr, et al. PLoS One, 2018. PMID 30286167, Free PMC Article
  2. Concomitant duplications of opioid peptide and receptor genes before the origin of jawed vertebrates. Sundström G, et al. PLoS One, 2010 May 6. PMID 20463905, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC175018

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
  
enables cytoskeletal protein binding IEA
Inferred from Electronic Annotation
more info
  
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cortical actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of excitatory synapse assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
band 4.1-like protein 3; band 4.1-like protein 3a
Names
zmp:0000000522

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003987.1 → NP_001003987.1  band 4.1-like protein 3a

    See identical proteins and their annotated locations for NP_001003987.1

    Status: PROVISIONAL

    Source sequence(s)
    BC080246
    UniProtKB/TrEMBL
    A0A8M9PLQ9, E7F0A7, E7F634, Q68EI5
    Related
    ENSDARP00000111490.2, ENSDART00000130310.3
    Conserved Domains (5) summary
    smart00295
    Location:92 → 281
    B41; Band 4.1 homologues
    cd13184
    Location:276 → 369
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:549 → 595
    SAB; SAB domain
    pfam05902
    Location:748 → 825
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:378 → 419
    FA; FERM adjacent (FA)

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007135.7 Reference GRCz11 Primary Assembly

    Range
    41927330..41986897
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021470148.1 → XP_021325823.1  band 4.1-like protein 3 isoform X4

    UniProtKB/TrEMBL
    A0A8M9P5U9
    Conserved Domains (6) summary
    smart00295
    Location:92 → 281
    B41; Band 4.1 homologues
    cd13184
    Location:276 → 384
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:564 → 610
    SAB; SAB domain
    pfam05902
    Location:1064 → 1169
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:393 → 434
    FA; FERM adjacent (FA)
    cl26247
    Location:604 → 780
    DNA_pol3_delta2; DNA polymerase III, delta subunit

  2. XM_021470142.1 → XP_021325817.1  band 4.1-like protein 3 isoform X1

    UniProtKB/TrEMBL
    A0A8M9P5U6
    Conserved Domains (6) summary
    smart00295
    Location:3 → 192
    B41; Band 4.1 homologues
    cd13184
    Location:187 → 295
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:475 → 521
    SAB; SAB domain
    pfam05902
    Location:975 → 1080
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:304 → 345
    FA; FERM adjacent (FA)
    cl26247
    Location:515 → 691
    DNA_pol3_delta2; DNA polymerase III, delta subunit

  3. XM_021470144.1 → XP_021325819.1  band 4.1-like protein 3 isoform X3

    UniProtKB/TrEMBL
    A0A8M9PLP9
    Conserved Domains (6) summary
    smart00295
    Location:3 → 192
    B41; Band 4.1 homologues
    cd13184
    Location:187 → 295
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:475 → 521
    SAB; SAB domain
    pfam05902
    Location:975 → 1052
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:304 → 345
    FA; FERM adjacent (FA)
    cl26247
    Location:515 → 691
    DNA_pol3_delta2; DNA polymerase III, delta subunit

  4. XM_021470143.1 → XP_021325818.1  band 4.1-like protein 3 isoform X2

    UniProtKB/TrEMBL
    A0A8M9PFY0
    Conserved Domains (6) summary
    smart00295
    Location:3 → 192
    B41; Band 4.1 homologues
    cd13184
    Location:187 → 280
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:460 → 506
    SAB; SAB domain
    pfam05902
    Location:960 → 1065
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:289 → 330
    FA; FERM adjacent (FA)
    cl26247
    Location:500 → 676
    DNA_pol3_delta2; DNA polymerase III, delta subunit

  5. XM_021470152.1 → XP_021325827.1  band 4.1-like protein 3 isoform X7

    UniProtKB/TrEMBL
    A0A8M9P5V2
    Conserved Domains (5) summary
    smart00295
    Location:3 → 192
    B41; Band 4.1 homologues
    cd13184
    Location:187 → 295
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:475 → 521
    SAB; SAB domain
    pfam05902
    Location:790 → 895
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:304 → 345
    FA; FERM adjacent (FA)

  6. XM_021470150.1 → XP_021325825.1  band 4.1-like protein 3 isoform X5

    UniProtKB/TrEMBL
    A0A8M9PXF4
    Conserved Domains (6) summary
    smart00295
    Location:3 → 192
    B41; Band 4.1 homologues
    cd13184
    Location:187 → 295
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:475 → 521
    SAB; SAB domain
    pfam05902
    Location:859 → 964
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:304 → 345
    FA; FERM adjacent (FA)
    cl26247
    Location:515 → 691
    DNA_pol3_delta2; DNA polymerase III, delta subunit

  7. XM_021470151.1 → XP_021325826.1  band 4.1-like protein 3 isoform X6

    UniProtKB/TrEMBL
    A0A8M9PU07
    Conserved Domains (6) summary
    smart00295
    Location:3 → 192
    B41; Band 4.1 homologues
    cd13184
    Location:187 → 295
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:475 → 521
    SAB; SAB domain
    pfam05902
    Location:859 → 936
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:304 → 345
    FA; FERM adjacent (FA)
    cl26247
    Location:515 → 691
    DNA_pol3_delta2; DNA polymerase III, delta subunit

  8. XM_021470145.1 → XP_021325820.1  band 4.1-like protein 3 isoform X4

    UniProtKB/TrEMBL
    A0A8M9P5U9
    Conserved Domains (6) summary
    smart00295
    Location:92 → 281
    B41; Band 4.1 homologues
    cd13184
    Location:276 → 384
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:564 → 610
    SAB; SAB domain
    pfam05902
    Location:1064 → 1169
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:393 → 434
    FA; FERM adjacent (FA)
    cl26247
    Location:604 → 780
    DNA_pol3_delta2; DNA polymerase III, delta subunit

  9. XM_021470153.1 → XP_021325828.1  band 4.1-like protein 3 isoform X8

    UniProtKB/TrEMBL
    A0A8M9PFZ0
    Conserved Domains (5) summary
    smart00295
    Location:92 → 281
    B41; Band 4.1 homologues
    cd13184
    Location:276 → 369
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:549 → 595
    SAB; SAB domain
    pfam05902
    Location:748 → 853
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:378 → 419
    FA; FERM adjacent (FA)

  10. XM_021470149.1 → XP_021325824.1  band 4.1-like protein 3 isoform X4

    UniProtKB/TrEMBL
    A0A8M9P5U9
    Conserved Domains (6) summary
    smart00295
    Location:92 → 281
    B41; Band 4.1 homologues
    cd13184
    Location:276 → 384
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:564 → 610
    SAB; SAB domain
    pfam05902
    Location:1064 → 1169
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:393 → 434
    FA; FERM adjacent (FA)
    cl26247
    Location:604 → 780
    DNA_pol3_delta2; DNA polymerase III, delta subunit

  11. XM_021470146.1 → XP_021325821.1  band 4.1-like protein 3 isoform X4

    UniProtKB/TrEMBL
    A0A8M9P5U9
    Conserved Domains (6) summary
    smart00295
    Location:92 → 281
    B41; Band 4.1 homologues
    cd13184
    Location:276 → 384
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:564 → 610
    SAB; SAB domain
    pfam05902
    Location:1064 → 1169
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:393 → 434
    FA; FERM adjacent (FA)
    cl26247
    Location:604 → 780
    DNA_pol3_delta2; DNA polymerase III, delta subunit

  12. XM_021470147.1 → XP_021325822.1  band 4.1-like protein 3 isoform X4

    UniProtKB/TrEMBL
    A0A8M9P5U9
    Conserved Domains (6) summary
    smart00295
    Location:92 → 281
    B41; Band 4.1 homologues
    cd13184
    Location:276 → 384
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:564 → 610
    SAB; SAB domain
    pfam05902
    Location:1064 → 1169
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:393 → 434
    FA; FERM adjacent (FA)
    cl26247
    Location:604 → 780
    DNA_pol3_delta2; DNA polymerase III, delta subunit

  13. XM_021470154.1 → XP_021325829.1  band 4.1-like protein 3 isoform X9

    UniProtKB/TrEMBL
    A0A8M9PLQ9, E7F0A7, E7F634, Q68EI5
    Related
    ENSDARP00000016443.8, ENSDART00000022349.9
    Conserved Domains (5) summary
    smart00295
    Location:92 → 281
    B41; Band 4.1 homologues
    cd13184
    Location:276 → 369
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:549 → 595
    SAB; SAB domain
    pfam05902
    Location:748 → 825
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:378 → 419
    FA; FERM adjacent (FA)

  14. XM_021470155.1 → XP_021325830.1  band 4.1-like protein 3 isoform X10

    UniProtKB/TrEMBL
    A0A8M9PXF8
    Conserved Domains (2) summary
    pfam04382
    Location:122 → 168
    SAB; SAB domain
    pfam05902
    Location:622 → 727
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
Nucleotide Protein Strain
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