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HSD17B12 hydroxysteroid 17-beta dehydrogenase 12 [ Canis lupus familiaris (dog) ]

Gene ID: 475939, updated on 5-Mar-2024

Summary

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Official Symbol
HSD17B12provided by VGNC
Official Full Name
hydroxysteroid 17-beta dehydrogenase 12provided by VGNC
Primary source
VGNC:VGNC:41802
See related
Ensembl:ENSCAFG00845018875
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See HSD17B12 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
11
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 18 NC_051822.1 (26529683..26683219, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 18 NC_006600.4 (25594145..25748413, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 18 NC_049239.1 (26296764..26451042, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 18 NC_049278.1 (26039150..26192361, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 18 NC_049759.1 (25684733..25839066, complement)

Chromosome 18 - NC_051822.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119864202 Neighboring gene alkB homolog 3, alpha-ketoglutarate dependent dioxygenase Neighboring gene transfer RNA lysine (anticodon CUU) Neighboring gene uncharacterized LOC111090926 Neighboring gene U6 spliceosomal RNA Neighboring gene 60S ribosomal protein L21-like Neighboring gene uncharacterized LOC119864204 Neighboring gene uncharacterized LOC111090927 Neighboring gene microRNA mir-129-2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
very-long-chain 3-oxoacyl-CoA reductase
XP_038279989.1
XP_038279990.1
XP_038309738.1
XP_038356343.1
XP_038356344.1
XP_038418909.1
XP_038418910.1
XP_038483030.1
XP_038483031.1
XP_848504.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051822.1 Reference ROS_Cfam_1.0

    Range
    26529683..26683219 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038424062.1 → XP_038279990.1  very-long-chain 3-oxoacyl-CoA reductase isoform X2

    Conserved Domains (1) summary
    cd05356
    Location:55 → 248
    17beta-HSD1_like_SDR_c; 17-beta-hydroxysteroid dehydrogenases (17beta-HSDs) types -1, -3, and -12, -like, classical (c) SDRs

  2. XM_038424061.1 → XP_038279989.1  very-long-chain 3-oxoacyl-CoA reductase isoform X1

    UniProtKB/TrEMBL
    A0A8C0MDV5, A0A8C0QWG9, A0A8C0SGC7, A0A8I3NX04, A0A8I3P3B7
    Related
    ENSCAFP00845026118.1, ENSCAFT00845033367.1
    Conserved Domains (2) summary
    cd05356
    Location:50 → 289
    17beta-HSD1_like_SDR_c; 17-beta-hydroxysteroid dehydrogenases (17beta-HSDs) types -1, -3, and -12, -like, classical (c) SDRs
    cl21454
    Location:10 → 84
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049278.1 Alternate UMICH_Zoey_3.1

    Range
    26039150..26192361 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038500416.1 → XP_038356344.1  very-long-chain 3-oxoacyl-CoA reductase isoform X2

    Conserved Domains (1) summary
    cd05356
    Location:55 → 248
    17beta-HSD1_like_SDR_c; 17-beta-hydroxysteroid dehydrogenases (17beta-HSDs) types -1, -3, and -12, -like, classical (c) SDRs

  2. XM_038500415.1 → XP_038356343.1  very-long-chain 3-oxoacyl-CoA reductase isoform X1

    Conserved Domains (2) summary
    cd05356
    Location:50 → 289
    17beta-HSD1_like_SDR_c; 17-beta-hydroxysteroid dehydrogenases (17beta-HSDs) types -1, -3, and -12, -like, classical (c) SDRs
    cl21454
    Location:10 → 84
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049759.1 Alternate UNSW_CanFamBas_1.0

    Range
    25684733..25839066 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038627103.1 → XP_038483031.1  very-long-chain 3-oxoacyl-CoA reductase isoform X2

    Conserved Domains (1) summary
    cd05356
    Location:55 → 248
    17beta-HSD1_like_SDR_c; 17-beta-hydroxysteroid dehydrogenases (17beta-HSDs) types -1, -3, and -12, -like, classical (c) SDRs

  2. XM_038627102.1 → XP_038483030.1  very-long-chain 3-oxoacyl-CoA reductase isoform X1

    Conserved Domains (2) summary
    cd05356
    Location:50 → 289
    17beta-HSD1_like_SDR_c; 17-beta-hydroxysteroid dehydrogenases (17beta-HSDs) types -1, -3, and -12, -like, classical (c) SDRs
    cl21454
    Location:10 → 84
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049239.1 Alternate UU_Cfam_GSD_1.0

    Range
    26296764..26451042 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038562982.1 → XP_038418910.1  very-long-chain 3-oxoacyl-CoA reductase isoform X2

    Conserved Domains (1) summary
    cd05356
    Location:55 → 248
    17beta-HSD1_like_SDR_c; 17-beta-hydroxysteroid dehydrogenases (17beta-HSDs) types -1, -3, and -12, -like, classical (c) SDRs

  2. XM_038562981.1 → XP_038418909.1  very-long-chain 3-oxoacyl-CoA reductase isoform X1

    UniProtKB/TrEMBL
    A0A8C0MDV5, A0A8C0QWG9, A0A8C0SGC7, A0A8I3NX04, A0A8I3P3B7
    Conserved Domains (2) summary
    cd05356
    Location:50 → 289
    17beta-HSD1_like_SDR_c; 17-beta-hydroxysteroid dehydrogenases (17beta-HSDs) types -1, -3, and -12, -like, classical (c) SDRs
    cl21454
    Location:10 → 84
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006600.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    25594145..25748413 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038453810.1 → XP_038309738.1  very-long-chain 3-oxoacyl-CoA reductase isoform X2

    Conserved Domains (1) summary
    cd05356
    Location:55 → 248
    17beta-HSD1_like_SDR_c; 17-beta-hydroxysteroid dehydrogenases (17beta-HSDs) types -1, -3, and -12, -like, classical (c) SDRs

  2. XM_843411.6 → XP_848504.1  very-long-chain 3-oxoacyl-CoA reductase isoform X1

    UniProtKB/TrEMBL
    A0A8C0MDV5, A0A8C0QWG9, A0A8C0SGC7, A0A8I3NX04, A0A8I3P3B7
    Conserved Domains (2) summary
    cd05356
    Location:50 → 289
    17beta-HSD1_like_SDR_c; 17-beta-hydroxysteroid dehydrogenases (17beta-HSDs) types -1, -3, and -12, -like, classical (c) SDRs
    cl21454
    Location:10 → 84
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
Nucleotide Protein
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