FRZB frizzled related protein [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: FRZBprovided by VGNC
Official Full Name: frizzled related proteinprovided by VGNC
Primary source: VGNC:VGNC:53094
See related: Ensembl:ENSCAFG00845016004
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 36

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	36	NC_051840.1 (26038918..26069318, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	36	NC_006618.4 (25782614..25812978, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	36	NC_049257.1 (26237636..26268037, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	36	NC_049296.1 (26165036..26195383, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	36	NC_049777.1 (26095997..26126346, complement)

Chromosome 36 - NC_051840.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables Wnt-protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in canonical Wnt signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in non-canonical Wnt signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: secreted frizzled-related protein 3

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051840.1 Reference ROS_Cfam_1.0

Range

26038918..26069318 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038446750.1 → XP_038302678.1 secreted frizzled-related protein 3

UniProtKB/TrEMBL

A0A8C0MQF3, A0A8C0TFQ9, A0A8I3NZA8

Related

ENSCAFP00845022453.1, ENSCAFT00845028539.1

Conserved Domains (2) summary

cd07441
Location:33 → 158

CRD_SFRP3; Cysteine-rich domain of the secreted frizzled-related protein 3 (SFRP3, alias FRZB), a Wnt antagonist

cd03581
Location:189 → 298

NTR_Sfrp3_like; NTR domain, Secreted frizzled-related protein (Sfrp) 3-like subfamily; composed of proteins similar to human Sfrp3 and Sfrp4. Sfrps are soluble proteins containing an NTR domain C-terminal to a cysteine-rich Frizzled domain. They show diverse functions ...

Alternate UMICH_Zoey_3.1

Genomic

NC_049296.1 Alternate UMICH_Zoey_3.1

Range

26165036..26195383 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038521367.1 → XP_038377295.1 secreted frizzled-related protein 3

Conserved Domains (2) summary

cd07441
Location:33 → 158

CRD_SFRP3; Cysteine-rich domain of the secreted frizzled-related protein 3 (SFRP3, alias FRZB), a Wnt antagonist

cd03581
Location:189 → 298

NTR_Sfrp3_like; NTR domain, Secreted frizzled-related protein (Sfrp) 3-like subfamily; composed of proteins similar to human Sfrp3 and Sfrp4. Sfrps are soluble proteins containing an NTR domain C-terminal to a cysteine-rich Frizzled domain. They show diverse functions ...

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049777.1 Alternate UNSW_CanFamBas_1.0

Range

26095997..26126346 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038648938.1 → XP_038504866.1 secreted frizzled-related protein 3

Conserved Domains (2) summary

cd07441
Location:33 → 158

CRD_SFRP3; Cysteine-rich domain of the secreted frizzled-related protein 3 (SFRP3, alias FRZB), a Wnt antagonist

cd03581
Location:189 → 298

NTR_Sfrp3_like; NTR domain, Secreted frizzled-related protein (Sfrp) 3-like subfamily; composed of proteins similar to human Sfrp3 and Sfrp4. Sfrps are soluble proteins containing an NTR domain C-terminal to a cysteine-rich Frizzled domain. They show diverse functions ...

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049257.1 Alternate UU_Cfam_GSD_1.0

Range

26237636..26268037 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038584521.1 → XP_038440449.1 secreted frizzled-related protein 3

UniProtKB/TrEMBL

A0A8C0MQF3, A0A8C0TFQ9, A0A8I3NZA8

Conserved Domains (2) summary

cd07441
Location:33 → 158

CRD_SFRP3; Cysteine-rich domain of the secreted frizzled-related protein 3 (SFRP3, alias FRZB), a Wnt antagonist

cd03581
Location:189 → 298

NTR_Sfrp3_like; NTR domain, Secreted frizzled-related protein (Sfrp) 3-like subfamily; composed of proteins similar to human Sfrp3 and Sfrp4. Sfrps are soluble proteins containing an NTR domain C-terminal to a cysteine-rich Frizzled domain. They show diverse functions ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006618.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

25782614..25812978 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038463238.1 → XP_038319166.1 secreted frizzled-related protein 3

UniProtKB/TrEMBL

A0A8C0MQF3, A0A8C0TFQ9, A0A8I3NZA8

Conserved Domains (2) summary

cd07441
Location:33 → 158

CRD_SFRP3; Cysteine-rich domain of the secreted frizzled-related protein 3 (SFRP3, alias FRZB), a Wnt antagonist

cd03581
Location:189 → 298

NTR_Sfrp3_like; NTR domain, Secreted frizzled-related protein (Sfrp) 3-like subfamily; composed of proteins similar to human Sfrp3 and Sfrp4. Sfrps are soluble proteins containing an NTR domain C-terminal to a cysteine-rich Frizzled domain. They show diverse functions ...