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P4HA1 prolyl 4-hydroxylase subunit alpha 1 [ Canis lupus familiaris (dog) ]

Gene ID: 479242, updated on 5-Mar-2024

Summary

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Official Symbol
P4HA1provided by VGNC
Official Full Name
prolyl 4-hydroxylase subunit alpha 1provided by VGNC
Primary source
VGNC:VGNC:44222
See related
Ensembl:ENSCAFG00845006050
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See P4HA1 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
18
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 4 NC_051808.1 (23886920..23964071, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 4 NC_006586.4 (23738890..23816335, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 4 NC_049225.1 (24339447..24416949, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 4 NC_049264.1 (23785865..23863342, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 4 NC_049745.1 (23984840..24062302, complement)

Chromosome 4 - NC_051808.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene protein AMN1 homolog Neighboring gene enolase-phosphatase E1-like Neighboring gene nudix hydrolase 13 Neighboring gene ecdysoneless cell cycle regulator Neighboring gene family with sequence similarity 149 member B1 Neighboring gene DnaJ heat shock protein family (Hsp40) member C9

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables L-ascorbic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables procollagen-proline 4-dioxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in peptidyl-proline hydroxylation to 4-hydroxy-L-proline IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
prolyl 4-hydroxylase subunit alpha-1
Names
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I
XP_005619063.1
XP_005619064.1
XP_038329170.1
XP_038329171.1
XP_038329172.1
XP_038390235.1
XP_038390236.1
XP_038390237.1
XP_038454554.1
XP_038454555.1
XP_038454556.1
XP_038518832.1
XP_038518833.1
XP_038518834.1
XP_850682.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051808.1 Reference ROS_Cfam_1.0

    Range
    23886920..23964071 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038662906.1 → XP_038518834.1  prolyl 4-hydroxylase subunit alpha-1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0PSC4, A0A8C0R7J4, A0A8I3N1J1
    Related
    ENSCAFP00845008361.1, ENSCAFT00845010723.1
    Conserved Domains (2) summary
    smart00702
    Location:345 → 518
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    pfam08336
    Location:25 → 112
    P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region

  2. XM_038662905.1 → XP_038518833.1  prolyl 4-hydroxylase subunit alpha-1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0MVU6, A0A8C0PN19, A0A8I3RT21, A0A8I3RUH8
    Conserved Domains (2) summary
    smart00702
    Location:345 → 518
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    pfam08336
    Location:25 → 112
    P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region

  3. XM_038662904.1 → XP_038518832.1  prolyl 4-hydroxylase subunit alpha-1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0MVU6, A0A8C0PN19, A0A8I3RT21, A0A8I3RUH8
    Related
    ENSCAFP00845008375.1, ENSCAFT00845010738.1
    Conserved Domains (2) summary
    smart00702
    Location:345 → 518
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    pfam08336
    Location:25 → 112
    P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region

RNA

  1. XR_005425556.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049264.1 Alternate UMICH_Zoey_3.1

    Range
    23785865..23863342 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038473244.1 → XP_038329172.1  prolyl 4-hydroxylase subunit alpha-1 isoform X2

    Conserved Domains (2) summary
    smart00702
    Location:345 → 518
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    pfam08336
    Location:25 → 112
    P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region

  2. XM_038473243.1 → XP_038329171.1  prolyl 4-hydroxylase subunit alpha-1 isoform X1

    Conserved Domains (2) summary
    smart00702
    Location:345 → 518
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    pfam08336
    Location:25 → 112
    P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region

  3. XM_038473242.1 → XP_038329170.1  prolyl 4-hydroxylase subunit alpha-1 isoform X1

    Conserved Domains (2) summary
    smart00702
    Location:345 → 518
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    pfam08336
    Location:25 → 112
    P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region

RNA

  1. XR_005324150.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049745.1 Alternate UNSW_CanFamBas_1.0

    Range
    23984840..24062302 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038598628.1 → XP_038454556.1  prolyl 4-hydroxylase subunit alpha-1 isoform X2

    Conserved Domains (2) summary
    smart00702
    Location:345 → 518
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    pfam08336
    Location:25 → 112
    P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region

  2. XM_038598627.1 → XP_038454555.1  prolyl 4-hydroxylase subunit alpha-1 isoform X1

    Conserved Domains (2) summary
    smart00702
    Location:345 → 518
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    pfam08336
    Location:25 → 112
    P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region

  3. XM_038598626.1 → XP_038454554.1  prolyl 4-hydroxylase subunit alpha-1 isoform X1

    Conserved Domains (2) summary
    smart00702
    Location:345 → 518
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    pfam08336
    Location:25 → 112
    P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region

RNA

  1. XR_005392466.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049225.1 Alternate UU_Cfam_GSD_1.0

    Range
    24339447..24416949 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038534309.1 → XP_038390237.1  prolyl 4-hydroxylase subunit alpha-1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0PSC4, A0A8C0R7J4, A0A8I3N1J1
    Conserved Domains (2) summary
    smart00702
    Location:345 → 518
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    pfam08336
    Location:25 → 112
    P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region

  2. XM_038534308.1 → XP_038390236.1  prolyl 4-hydroxylase subunit alpha-1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0MVU6, A0A8C0PN19, A0A8I3RT21, A0A8I3RUH8
    Conserved Domains (2) summary
    smart00702
    Location:345 → 518
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    pfam08336
    Location:25 → 112
    P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region

  3. XM_038534307.1 → XP_038390235.1  prolyl 4-hydroxylase subunit alpha-1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0MVU6, A0A8C0PN19, A0A8I3RT21, A0A8I3RUH8
    Conserved Domains (2) summary
    smart00702
    Location:345 → 518
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    pfam08336
    Location:25 → 112
    P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region

RNA

  1. XR_005357958.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006586.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    23738890..23816335 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005619007.4 → XP_005619064.1  prolyl 4-hydroxylase subunit alpha-1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0PSC4, A0A8C0R7J4, A0A8I3N1J1
    Conserved Domains (2) summary
    smart00702
    Location:345 → 518
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    pfam08336
    Location:25 → 112
    P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region

  2. XM_005619006.4 → XP_005619063.1  prolyl 4-hydroxylase subunit alpha-1 isoform X1

    See identical proteins and their annotated locations for XP_005619063.1

    UniProtKB/TrEMBL
    A0A8C0MVU6, A0A8C0PN19, A0A8I3RT21, A0A8I3RUH8
    Conserved Domains (2) summary
    smart00702
    Location:345 → 518
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    pfam08336
    Location:25 → 112
    P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region

  3. XM_845589.6 → XP_850682.1  prolyl 4-hydroxylase subunit alpha-1 isoform X1

    See identical proteins and their annotated locations for XP_850682.1

    UniProtKB/TrEMBL
    A0A8C0MVU6, A0A8C0PN19, A0A8I3RT21, A0A8I3RUH8
    Conserved Domains (2) summary
    smart00702
    Location:345 → 518
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    pfam08336
    Location:25 → 112
    P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region

RNA

  1. XR_002625716.2 RNA Sequence

Nucleotide Protein
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