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MVK mevalonate kinase [ Canis lupus familiaris (dog) ]

Gene ID: 486309, updated on 5-Mar-2024

Summary

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Official Symbol
MVKprovided by VGNC
Official Full Name
mevalonate kinaseprovided by VGNC
Primary source
VGNC:VGNC:43509
See related
Ensembl:ENSCAFG00845022604
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See MVK in Genome Data Viewer
Location:
chromosome: 26
Exon count:
12
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 26 NC_051830.1 (17839721..17861223, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 26 NC_006608.4 (18284429..18305927)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 26 NC_049247.1 (17848229..17869727, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 26 NC_049286.1 (18493628..18515091)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 26 NC_049767.1 (17830226..17851709, complement)

Chromosome 26 - NC_051830.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119866094 Neighboring gene uncharacterized LOC106557805 Neighboring gene metabolism of cobalamin associated B Neighboring gene uncharacterized LOC111092706

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mevalonate kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cholesterol biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in isoprenoid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mevalonate kinase
Names
mevalonate kinase (mevalonic aciduria)
XP_005636378.2
XP_005636379.2
XP_038292914.1
XP_038292915.1
XP_038314945.1
XP_038367832.1
XP_038367833.1
XP_038431323.1
XP_038431324.1
XP_038495505.1
XP_038495506.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051830.1 Reference ROS_Cfam_1.0

    Range
    17839721..17861223 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038436986.1 → XP_038292914.1  mevalonate kinase isoform X1

    UniProtKB/TrEMBL
    A0A8C0L6D2, A0A8C0NYF9, A0A8I3PG05, A0A8P0STR6
    Conserved Domains (1) summary
    cl40731
    Location:10 → 388
    PLN02677; mevalonate kinase

  2. XM_038436987.1 → XP_038292915.1  mevalonate kinase isoform X1

    UniProtKB/TrEMBL
    A0A8C0L6D2, A0A8C0NYF9, A0A8I3PG05, A0A8P0STR6
    Related
    ENSCAFP00845031252.1, ENSCAFT00845039910.1
    Conserved Domains (1) summary
    cl40731
    Location:10 → 388
    PLN02677; mevalonate kinase

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049286.1 Alternate UMICH_Zoey_3.1

    Range
    18493628..18515091
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038511904.1 → XP_038367832.1  mevalonate kinase isoform X1

    Conserved Domains (1) summary
    cl40731
    Location:10 → 388
    PLN02677; mevalonate kinase

  2. XM_038511905.1 → XP_038367833.1  mevalonate kinase isoform X1

    Conserved Domains (1) summary
    cl40731
    Location:10 → 388
    PLN02677; mevalonate kinase

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049767.1 Alternate UNSW_CanFamBas_1.0

    Range
    17830226..17851709 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038639577.1 → XP_038495505.1  mevalonate kinase isoform X1

    Conserved Domains (1) summary
    cl40731
    Location:10 → 388
    PLN02677; mevalonate kinase

  2. XM_038639578.1 → XP_038495506.1  mevalonate kinase isoform X1

    Conserved Domains (1) summary
    cl40731
    Location:10 → 388
    PLN02677; mevalonate kinase

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049247.1 Alternate UU_Cfam_GSD_1.0

    Range
    17848229..17869727 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038575395.1 → XP_038431323.1  mevalonate kinase isoform X1

    UniProtKB/TrEMBL
    A0A8C0L6D2, A0A8C0NYF9, A0A8I3PG05, A0A8P0STR6
    Conserved Domains (1) summary
    cl40731
    Location:10 → 388
    PLN02677; mevalonate kinase

  2. XM_038575396.1 → XP_038431324.1  mevalonate kinase isoform X1

    UniProtKB/TrEMBL
    A0A8C0L6D2, A0A8C0NYF9, A0A8I3PG05, A0A8P0STR6
    Conserved Domains (1) summary
    cl40731
    Location:10 → 388
    PLN02677; mevalonate kinase

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006608.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    18284429..18305927
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005636321.4 → XP_005636378.2  mevalonate kinase isoform X2

    UniProtKB/TrEMBL
    A0A8I3S398
    Conserved Domains (1) summary
    cl40731
    Location:10 → 336
    PLN02677; mevalonate kinase

  2. XM_005636322.2 → XP_005636379.2  mevalonate kinase isoform X2

    UniProtKB/TrEMBL
    A0A8I3S398
    Conserved Domains (1) summary
    cl40731
    Location:10 → 336
    PLN02677; mevalonate kinase

  3. XM_038459017.1 → XP_038314945.1  mevalonate kinase isoform X3

    UniProtKB/TrEMBL
    A0A8C0L6D2, A0A8C0NYF9, A0A8I3PG05, A0A8P0STR6
    Conserved Domains (1) summary
    cl40731
    Location:10 → 388
    PLN02677; mevalonate kinase
Nucleotide Protein
Heading Accession and Version

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