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BIRC3 baculoviral IAP repeat containing 3 [ Canis lupus familiaris (dog) ]

Gene ID: 489433, updated on 22-Jan-2024

Summary

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Official Symbol
BIRC3provided by VGNC
Official Full Name
baculoviral IAP repeat containing 3provided by VGNC
Primary source
VGNC:VGNC:53305
See related
Ensembl:ENSCAFG00845001106
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
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Genomic context

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See BIRC3 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
12
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 5 NC_051809.1 (29377538..29396454, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 5 NC_006587.4 (29274261..29286176, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 5 NC_049226.1 (29466940..29478850, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 5 NC_049265.1 (29434557..29446661, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 5 NC_049746.1 (29292001..29303913, complement)

Chromosome 5 - NC_051809.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 123 Neighboring gene baculoviral IAP repeat containing 2 Neighboring gene uncharacterized LOC111096105 Neighboring gene uncharacterized LOC102153712

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type endopeptidase inhibitor activity involved in apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in spindle microtubule IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
baculoviral IAP repeat-containing protein 3
Names
RING-type E3 ubiquitin transferase BIRC3
NP_001074194.1
XP_038520078.1
XP_038520079.1
XP_038520080.1
XP_038520081.1
XP_038520082.1
XP_038520083.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080725.1 → NP_001074194.1  baculoviral IAP repeat-containing protein 3

    See identical proteins and their annotated locations for NP_001074194.1

    Status: PROVISIONAL

    Source sequence(s)
    EF102104
    UniProtKB/Swiss-Prot
    A1E2V0
    UniProtKB/TrEMBL
    A0A8C0K9X4, A0A8C0KAQ3
    Conserved Domains (6) summary
    smart00238
    Location:254 → 322
    BIR; Baculoviral inhibition of apoptosis protein repeat
    cd14394
    Location:377 → 421
    UBA_BIRC2_3; UBA domain found in baculoviral IAP repeat-containing protein BIRC2, BIRC3 and similar proteins
    cd16713
    Location:551 → 604
    RING-HC_BIRC2_3_7; RING finger, HC subclass, found in apoptosis protein c-IAP1, c-IAP2, livin, and similar proteins
    cl25686
    Location:308 → 380
    COG5135; Uncharacterized protein [Function unknown]
    pfam00653
    Location:172 → 236
    BIR; Inhibitor of Apoptosis domain
    cl14633
    Location:440 → 530
    DD; Death Domain Superfamily of protein-protein interaction domains

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051809.1 Reference ROS_Cfam_1.0

    Range
    29377538..29396454 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038664153.1 → XP_038520081.1  baculoviral IAP repeat-containing protein 3 isoform X1

    UniProtKB/Swiss-Prot
    A1E2V0
    UniProtKB/TrEMBL
    A0A8C0K9X4, A0A8C0KAQ3
    Conserved Domains (6) summary
    smart00238
    Location:254 → 322
    BIR; Baculoviral inhibition of apoptosis protein repeat
    cd14394
    Location:377 → 421
    UBA_BIRC2_3; UBA domain found in baculoviral IAP repeat-containing protein BIRC2, BIRC3 and similar proteins
    cd16713
    Location:551 → 604
    RING-HC_BIRC2_3_7; RING finger, HC subclass, found in apoptosis protein c-IAP1, c-IAP2, livin, and similar proteins
    cl25686
    Location:308 → 380
    COG5135; Uncharacterized protein [Function unknown]
    pfam00653
    Location:172 → 236
    BIR; Inhibitor of Apoptosis domain
    cl14633
    Location:440 → 530
    DD; Death Domain Superfamily of protein-protein interaction domains

  2. XM_038664154.1 → XP_038520082.1  baculoviral IAP repeat-containing protein 3 isoform X1

    UniProtKB/Swiss-Prot
    A1E2V0
    UniProtKB/TrEMBL
    A0A8C0K9X4, A0A8C0KAQ3
    Related
    ENSCAFP00845001493.1, ENSCAFT00845001898.1
    Conserved Domains (6) summary
    smart00238
    Location:254 → 322
    BIR; Baculoviral inhibition of apoptosis protein repeat
    cd14394
    Location:377 → 421
    UBA_BIRC2_3; UBA domain found in baculoviral IAP repeat-containing protein BIRC2, BIRC3 and similar proteins
    cd16713
    Location:551 → 604
    RING-HC_BIRC2_3_7; RING finger, HC subclass, found in apoptosis protein c-IAP1, c-IAP2, livin, and similar proteins
    cl25686
    Location:308 → 380
    COG5135; Uncharacterized protein [Function unknown]
    pfam00653
    Location:172 → 236
    BIR; Inhibitor of Apoptosis domain
    cl14633
    Location:440 → 530
    DD; Death Domain Superfamily of protein-protein interaction domains

  3. XM_038664151.1 → XP_038520079.1  baculoviral IAP repeat-containing protein 3 isoform X1

    UniProtKB/Swiss-Prot
    A1E2V0
    UniProtKB/TrEMBL
    A0A8C0K9X4, A0A8C0KAQ3
    Conserved Domains (6) summary
    smart00238
    Location:254 → 322
    BIR; Baculoviral inhibition of apoptosis protein repeat
    cd14394
    Location:377 → 421
    UBA_BIRC2_3; UBA domain found in baculoviral IAP repeat-containing protein BIRC2, BIRC3 and similar proteins
    cd16713
    Location:551 → 604
    RING-HC_BIRC2_3_7; RING finger, HC subclass, found in apoptosis protein c-IAP1, c-IAP2, livin, and similar proteins
    cl25686
    Location:308 → 380
    COG5135; Uncharacterized protein [Function unknown]
    pfam00653
    Location:172 → 236
    BIR; Inhibitor of Apoptosis domain
    cl14633
    Location:440 → 530
    DD; Death Domain Superfamily of protein-protein interaction domains

  4. XM_038664155.1 → XP_038520083.1  baculoviral IAP repeat-containing protein 3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KAQ3
    Conserved Domains (5) summary
    smart00238
    Location:254 → 322
    BIR; Baculoviral inhibition of apoptosis protein repeat
    cd16713
    Location:470 → 523
    RING-HC_BIRC2_3_7; RING finger, HC subclass, found in apoptosis protein c-IAP1, c-IAP2, livin, and similar proteins
    cl25686
    Location:308 → 360
    COG5135; Uncharacterized protein [Function unknown]
    pfam00653
    Location:172 → 236
    BIR; Inhibitor of Apoptosis domain
    cl14633
    Location:358 → 449
    DD; Death Domain Superfamily of protein-protein interaction domains

  5. XM_038664150.1 → XP_038520078.1  baculoviral IAP repeat-containing protein 3 isoform X1

    UniProtKB/Swiss-Prot
    A1E2V0
    UniProtKB/TrEMBL
    A0A8C0K9X4, A0A8C0KAQ3
    Conserved Domains (6) summary
    smart00238
    Location:254 → 322
    BIR; Baculoviral inhibition of apoptosis protein repeat
    cd14394
    Location:377 → 421
    UBA_BIRC2_3; UBA domain found in baculoviral IAP repeat-containing protein BIRC2, BIRC3 and similar proteins
    cd16713
    Location:551 → 604
    RING-HC_BIRC2_3_7; RING finger, HC subclass, found in apoptosis protein c-IAP1, c-IAP2, livin, and similar proteins
    cl25686
    Location:308 → 380
    COG5135; Uncharacterized protein [Function unknown]
    pfam00653
    Location:172 → 236
    BIR; Inhibitor of Apoptosis domain
    cl14633
    Location:440 → 530
    DD; Death Domain Superfamily of protein-protein interaction domains

  6. XM_038664152.1 → XP_038520080.1  baculoviral IAP repeat-containing protein 3 isoform X1

    UniProtKB/Swiss-Prot
    A1E2V0
    UniProtKB/TrEMBL
    A0A8C0K9X4, A0A8C0KAQ3
    Conserved Domains (6) summary
    smart00238
    Location:254 → 322
    BIR; Baculoviral inhibition of apoptosis protein repeat
    cd14394
    Location:377 → 421
    UBA_BIRC2_3; UBA domain found in baculoviral IAP repeat-containing protein BIRC2, BIRC3 and similar proteins
    cd16713
    Location:551 → 604
    RING-HC_BIRC2_3_7; RING finger, HC subclass, found in apoptosis protein c-IAP1, c-IAP2, livin, and similar proteins
    cl25686
    Location:308 → 380
    COG5135; Uncharacterized protein [Function unknown]
    pfam00653
    Location:172 → 236
    BIR; Inhibitor of Apoptosis domain
    cl14633
    Location:440 → 530
    DD; Death Domain Superfamily of protein-protein interaction domains

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049265.1 Alternate UMICH_Zoey_3.1

    Range
    29434557..29446661 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049746.1 Alternate UNSW_CanFamBas_1.0

    Range
    29292001..29303913 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049226.1 Alternate UU_Cfam_GSD_1.0

    Range
    29466940..29478850 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006587.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    29274261..29286176 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A1E2V0.1 GenPept UniProtKB/Swiss-Prot:A1E2V0

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